Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50012465
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM19264(CHEMBL866 | Myfortic | (4E)-6-(4-hydroxy-6-methoxy...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119113(1-{3-[N'-(3-Methoxy-4-oxazol-5-yl-phenyl)-N''-cyan...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119045(1-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-m-tolyl-urea ...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119128({3-[N'-(3-Methoxy-4-oxazol-5-yl-phenyl)-N''-cyano-...)
Affinity DataIC50: 110nMAssay Description:The compound was tested for it's in vitro inhibitor potency against inosine monophosphate dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119120(N-Butyl-3-[N'-(3-methoxy-4-oxazol-5-yl-phenyl)-N''...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119127(1-{3-[N'-(3-Methoxy-4-oxazol-5-yl-phenyl)-N''-cyan...)
Affinity DataIC50: 180nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119119(N''-cyano-N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-...)
Affinity DataIC50: 240nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119130(N''-cyano-N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119126(N''-cyano-N-[3-(hydroxymethyl)phenyl]-N'-[3-methox...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119115(N''-cyano-N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-...)
Affinity DataIC50: 320nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119114(N''-cyano-N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]g...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119121(N''-cyano-N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-...)
Affinity DataIC50: 340nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119124({3-[N'-(3-Methoxy-4-oxazol-5-yl-phenyl)-N''-cyano-...)
Affinity DataIC50: 340nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119110(N-(3-Methoxy-4-oxazol-5-yl-phenyl)-N'-cyano-N''-[3...)
Affinity DataIC50: 380nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119111(N''-methoxy-N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl...)
Affinity DataIC50: 660nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119129(ethyl(1E)-[(3-methoxy-4-oxazole-5-yl-phenyl)amino]...)
Affinity DataIC50: 740nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119123(N-Benzoyl-N'-(3-methoxy-4-oxazol-5-yl-phenyl)-guan...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119118(N-Acetyl-N'-(3-methoxy-4-oxazol-5-yl-phenyl)-N''-m...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119125(N''-cyano-N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119112(N''-cyano-N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119122(N''-cyano-N-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-...)
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119116(N-(3-Methoxy-4-oxazol-5-yl-phenyl)-N'-methyl-N''-m...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50119117(N-(3-Methoxy-4-oxazol-5-yl-phenyl)-N'-m-tolyl-guan...)
Affinity DataIC50: 3.00E+3nMAssay Description:The compound was tested for it's in vitro inhibitor potency against inosine monophosphate dehydrogenase II (IMPDH II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed