Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50048531
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067796BDBM50067796(L-374087 | N-(6-Amino-2-methyl-pyridin-3-ylmethyl)...)
Affinity DataKi:  0.700nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067797BDBM50067797(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methy...)
Affinity DataKi:  1nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215314BDBM50215314(CHEMBL100049)
Affinity DataKi:  2.5nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215447BDBM50215447(CHEMBL101867)
Affinity DataKi:  2.90nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100973BDBM50100973(CHEMBL101605)
Affinity DataKi:  3.10nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215308BDBM50215308(CHEMBL99185)
Affinity DataKi:  3.90nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50105480BDBM50105480(CHEMBL98194)
Affinity DataKi:  4.10nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215441BDBM50215441(CHEMBL101562)
Affinity DataKi:  5nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100974BDBM50100974(CHEMBL317739)
Affinity DataKi:  5.70nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215310BDBM50215310(CHEMBL97869)
Affinity DataKi:  6.5nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215311BDBM50215311(CHEMBL317140)
Affinity DataKi:  9nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100975BDBM50100975(CHEMBL100838)
Affinity DataKi:  9.30nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215302BDBM50215302(CHEMBL98057)
Affinity DataKi:  10nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216995BDBM50216995(CHEMBL319815)
Affinity DataKi:  10nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215304BDBM50215304(CHEMBL98212)
Affinity DataKi:  15nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215317BDBM50215317(CHEMBL97950)
Affinity DataKi:  16nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124087BDBM50124087(N-(1H-Benzoimidazol-5-ylmethyl)-2-(6-methyl-2-oxo-...)
Affinity DataKi:  17nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215318BDBM50215318(CHEMBL101613)
Affinity DataKi:  18nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216992BDBM50216992(CHEMBL98859)
Affinity DataKi:  18nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215315BDBM50215315(CHEMBL100843)
Affinity DataKi:  24nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215305BDBM50215305(CHEMBL100443)
Affinity DataKi:  26nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215309BDBM50215309(CHEMBL102193)
Affinity DataKi:  29nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100972BDBM50100972(CHEMBL98152)
Affinity DataKi:  30nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215306BDBM50215306(CHEMBL100565)
Affinity DataKi:  31nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215313BDBM50215313(CHEMBL101669)
Affinity DataKi:  33nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215442BDBM50215442(CHEMBL99116)
Affinity DataKi:  73nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216994BDBM50216994(CHEMBL99206)
Affinity DataKi:  74nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215316BDBM50215316(CHEMBL98281)
Affinity DataKi:  82nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216991BDBM50216991(CHEMBL318472)
Affinity DataKi:  89nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100976BDBM50100976(CHEMBL318241)
Affinity DataKi:  203nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215303BDBM50215303(CHEMBL317400)
Affinity DataKi:  224nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50217047BDBM50217047(CHEMBL318785)
Affinity DataKi:  224nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100970BDBM50100970(CHEMBL97975)
Affinity DataKi:  271nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215443BDBM50215443(CHEMBL100235)
Affinity DataKi:  444nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100967BDBM50100967(CHEMBL101615)
Affinity DataKi:  1.32E+3nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215440BDBM50215440(CHEMBL329976)
Affinity DataKi:  1.59E+3nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215307BDBM50215307(CHEMBL99279)
Affinity DataKi:  1.59E+3nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100968BDBM50100968(CHEMBL101262)
Affinity DataKi:  3.57E+3nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215439BDBM50215439(CHEMBL100837)
Affinity DataKi: >3.97E+3nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50216993BDBM50216993(CHEMBL101418)
Affinity DataKi: >3.97E+3nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215415BDBM50215415(CHEMBL98951)
Affinity DataKi:  1.24E+4nMAssay Description:In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed