Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50037077
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118719(7-Amino-3-{[1-(2-amino-3-cyclohexyl-propionyl)-pyr...)
Affinity DataKi:  0.140nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118730(7-Amino-3-(2-{[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.210nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118739(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.290nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118728(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.290nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118732(1-(2-Amino-3-phenyl-propionyl)-pyrrolidine-2-carbo...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118729(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.330nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118731(2-((R)-1-((S)-2-(((S)-6-amino-1-(oxazol-2-yl)-1-ox...)
Affinity DataKi:  0.420nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118735(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.5nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118738(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.820nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118718({2-[2-(5-Amino-1-phenethylaminooxalyl-pentylcarbam...)
Affinity DataKi:  0.840nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118723(N-[14-Benzyl-18-(3-guanidino-propyl)-11-(4-hydroxy...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118727(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  1.10nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118720(7-Amino-3-{[1-(2-amino-3-phenyl-propionyl)-pyrroli...)
Affinity DataKi:  1.40nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999 | U...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118717((S)-N-((S)-6-amino-1-oxo-1-(thiazol-2-yl)hexan-2-y...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118737(2-((R)-1-((S)-2-(((S)-6-amino-1-oxo-1-(thiazol-2-y...)
Affinity DataKi:  2.60nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118721((S)-N-((S)-6-amino-1-oxo-1-(thiazol-2-yl)hexan-2-y...)
Affinity DataKi:  3.5nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118722(2-Amino-N-{[5-amino-1-(thiazole-2-carbonyl)-pentyl...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118725(7-Amino-3-{[1-(3-carboxy-2-phenylmethanesulfonylam...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50038001(CHEMBL1166 | (2R,4S)-1-[5-Guanidino-2-(3-methyl-1,...)
Affinity DataKi:  19nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118734(6-Amino-2-[2-(5-{[1-(2-amino-3-phenyl-propionyl)-p...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118724((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  146nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118716(1-(3,3-Diphenyl-propionyl)-pyrrolidine-2-carboxyli...)
Affinity DataKi:  204nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118715(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  376nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118714(7-Methoxy-naphthalene-2-sulfonic acid [5-amino-1-(...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118736(7-Methoxy-naphthalene-2-sulfonic acid [5-amino-1-(...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118733(1-(3,3-Diphenyl-propionyl)-pyrrolidine-2-carboxyli...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50118726(N-[5-Amino-1-(thiazole-2-carbonyl)-pentyl]-2-(cycl...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed