Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 1281
TargetAcetylcholinesterase(Pacific electric ray)
Weizmann Institute of Science

LigandPNGBDBM10441((+)-Huperzine A | (13E)-1-amino-13-ethylidene-11-m...)
Affinity DataKi:  175nM ΔG°:  -38.6kJ/molepH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Weizmann Institute of Science

LigandPNGBDBM10632((1R,10R)-16-methyl-6,14-diazatetracyclo[7.5.3.0^{1...)
Affinity DataKi:  334nM ΔG°:  -37.0kJ/molepH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Weizmann Institute of Science

LigandPNGBDBM10441((+)-Huperzine A | (13E)-1-amino-13-ethylidene-11-m...)
Affinity DataKi:  4.30E+3nM ΔG°:  -30.6kJ/molepH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed