Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50012358
TargetType-1 angiotensin II receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117909(N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimet...)
Affinity DataIC50: 13nMAssay Description:Compound was evaluated for inhibitory activity against human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117909(N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimet...)
Affinity DataIC50: 24nMAssay Description:Compound was evaluated for inhibitory activity against human Endothelin A receptor (ETA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117909(N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimet...)
Affinity DataIC50: 60nMAssay Description:Compound was evaluated for inhibitory activity against human Endothelin B receptor (ETB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50042235(2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4...)
Affinity DataKi: >0.000100nMAssay Description:Compound was evaluated for its binding affinity towards human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091105(4'-Oxazol-2-yl-biphenyl-2-sulfonicacid(3,4-dimethy...)
Affinity DataKi: >0.000100nMAssay Description:Compound was evaluated for its binding affinity towards human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor B(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091105(4'-Oxazol-2-yl-biphenyl-2-sulfonicacid(3,4-dimethy...)
Affinity DataKi: >0.000100nMAssay Description:Compound was evaluated for its binding affinity towards rat Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor B(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50042235(2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4...)
Affinity DataKi:  0.800nMAssay Description:Compound was evaluated for its binding affinity towards rat Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50042235(2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4...)
Affinity DataKi:  1.10nMAssay Description:Compound was evaluated for its binding affinity towards human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50091105(4'-Oxazol-2-yl-biphenyl-2-sulfonicacid(3,4-dimethy...)
Affinity DataKi:  1.40nMAssay Description:Compound was evaluated for its binding affinity towards human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117910(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-y...)
Affinity DataKi:  1.90nMAssay Description:Compound was evaluated for its binding affinity towards human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor B(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117911(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-y...)
Affinity DataKi:  4.70nMAssay Description:Compound was evaluated for its binding affinity towards rat Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor B(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117910(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-y...)
Affinity DataKi:  6nMAssay Description:Compound was evaluated for its binding affinity towards rat Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117910(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-y...)
Affinity DataKi:  10nMAssay Description:Compound was evaluated for its binding affinity towards human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50117911(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-y...)
Affinity DataKi:  39nMAssay Description:Compound was evaluated for its binding affinity towards human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed