Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50012282
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116913((S)-4-(1-Furo[3,2-c]pyridin-2-yl-1-methyl-ethyl)-1...)
Affinity DataIC50: 0.0750nMAssay Description:Inhibitory concentration required to inhibit cleavage of a substrate by the wild-type HIV-1 protease enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116914((S)-4-(1-Furo[3,2-c]pyridin-2-yl-1-methyl-ethyl)-1...)
Affinity DataIC50: 0.150nMAssay Description:Inhibitory concentration required to inhibit cleavage of a substrate by the wild-type HIV-1 protease enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116915((S)-4-Furo[3,2-c]pyridin-2-ylmethyl-1-[(2S,4R)-2-h...)
Affinity DataIC50: 0.230nMAssay Description:Inhibitory concentration required to inhibit cleavage of a substrate by the wild-type HIV-1 protease enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM517(Crixivan | CHEMBL115 | L-735, 524 | MK639 | Indina...)
Affinity DataIC50: 0.590nMAssay Description:Inhibitory concentration required to inhibit cleavage of a substrate by the wild-type HIV-1 protease enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116916((S)-1-[(2S,4R)-2-Hydroxy-4-((1S,2R)-2-hydroxy-inda...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory concentration required to inhibit cleavage of a substrate by the wild-type HIV-1 protease enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed