Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50012272
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataEC50:  1.5nMAssay Description:Effective concentration required for agonistic activity against human D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Rat)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration required for agonistic activity against rat D2 long receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration required for agonistic activity against rat D2 short receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataEC50:  12nMAssay Description:Effective concentration required for agonistic activity against rat D2 short receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116767(Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indaz...)
Affinity DataEC50:  16nMAssay Description:Effective concentration required for agonistic activity against rat Dopamine receptor D2LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataEC50:  9.20nMAssay Description:Effective concentration required for agonistic activity against rat D2 short receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration required for agonistic activity against human D4.2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50010617(Preclamol | (-)-3-(1-Propyl-piperidin-3-yl)-phenol...)
Affinity DataEC50:  19nMAssay Description:Effective concentration required for agonistic activity against rat D2 long receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKd:  1.60nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116767(Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indaz...)
Affinity DataEC50:  47nMAssay Description:Effective concentration required for agonistic activity against rat D2 short receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50010617(Preclamol | (-)-3-(1-Propyl-piperidin-3-yl)-phenol...)
Affinity DataEC50:  60nMAssay Description:Effective concentration required for agonistic activity against human D4.2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116767(Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indaz...)
Affinity DataEC50:  2.80nMAssay Description:Effective concentration required for agonistic activity against human Dopamine receptor D3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataEC50:  15nMAssay Description:Effective concentration required for agonistic activity against human D4.2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration required for agonistic activity against human D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50010617(Preclamol | (-)-3-(1-Propyl-piperidin-3-yl)-phenol...)
Affinity DataEC50:  9.80nMAssay Description:Effective concentration required for agonistic activity against human D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50010617(Preclamol | (-)-3-(1-Propyl-piperidin-3-yl)-phenol...)
Affinity DataEC50:  19nMAssay Description:Effective concentration required for agonistic activity against rat D2 short receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116767(Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indaz...)
Affinity DataEC50:  430nMAssay Description:Effective concentration required for agonistic activity against human D4.2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116767(Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indaz...)
Affinity DataKi:  0.540nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human Dopamine receptor D3 (high/low affinity is given as 0.54/59)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  0.870nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human Dopamine receptor D3 (high/low affinity is given as 0.87/44)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D4.4 (high/low affinity is given as 8.5/130)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116767(Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indaz...)
Affinity DataKi:  8.60nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50010617(Preclamol | (-)-3-(1-Propyl-piperidin-3-yl)-phenol...)
Affinity DataKi:  9nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D2 long (high/low affinity is given as 9.0/1800)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  16nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human Dopamine receptor D3 (high/low affinity is given as 16/16000)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50010617(Preclamol | (-)-3-(1-Propyl-piperidin-3-yl)-phenol...)
Affinity DataKi:  16nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D4.4 (high/low affinity is given as 16/1300)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116767(Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indaz...)
Affinity DataKi:  18nMAssay Description:Binding affinity of compound measured against Dopamine receptor D1 from bovine striatal membranes using radioligand [3H]-SCH- 23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50010617(Preclamol | (-)-3-(1-Propyl-piperidin-3-yl)-phenol...)
Affinity DataKi:  25nMAssay Description:Binding affinity of compound measured using [3H]-spiperone for the cloned human Dopamine receptor D3 (high/low affinity is given as 25/1600)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50010617(Preclamol | (-)-3-(1-Propyl-piperidin-3-yl)-phenol...)
Affinity DataKi:  27nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D2 short (high/low affinity is given as 27/1800)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  27nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D2 short (high/low affinity is given as 35/3700)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116767(Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indaz...)
Affinity DataKi:  35nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D2 short (high/low affinity is given as 35/3700)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKi:  40nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D2 short (high/low affinity is given as 40/3600)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116767(Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indaz...)
Affinity DataKi:  50nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D4.4 (high/low affinity is given as 50/2200)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50010617(Preclamol | (-)-3-(1-Propyl-piperidin-3-yl)-phenol...)
Affinity DataKi:  52nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116767(Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indaz...)
Affinity DataKi:  85nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human Dopamine receptor D2L (high/low affinity is given as 85/6400)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  87nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D4.4 (high/low affinity is given as 87/23000)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  130nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D2 short (high/low affinity is given as 130/50000)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  230nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D2 long (high/low affinity is given as 230/53000)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116767(Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indaz...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity of compound measured for 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT-labeled porcine brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  3.10E+3nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  2.10E+4nMAssay Description:Binding affinity of compound measured against Dopamine receptor D1 from bovine striatal membranes using radioligand [3H]-SCH- 23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed