Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 4031
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Universite Paul Sabatier

LigandPNGBDBM43828(SMR000154162 | 2-[(4-fluorophenyl)methylthio]-N-(4...)
Affinity DataIC50: 8.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Universite Paul Sabatier

LigandPNGBDBM43835(N-cyclohexyl-5-nitro-2-(1-piperidinyl)benzamide | ...)
Affinity DataKi:  2.80E+3nM ΔG°:  -31.7kJ/mole IC50: 5.00E+5nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Universite Paul Sabatier

LigandPNGBDBM43833(SMR000185773 | N''''-(5,5-dimethyl-3-oxocyclohexen...)
Affinity DataKi:  8.00E+3nM ΔG°:  -29.1kJ/mole IC50: 2.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Universite Paul Sabatier

LigandPNGBDBM43832(diethyl 2-phenyl-1,1-cyclopropanedicarboxylate | c...)
Affinity DataKi:  1.90E+4nM ΔG°:  -26.9kJ/mole IC50: 4.00E+5nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Universite Paul Sabatier

LigandPNGBDBM43834(2-methoxy-6-nitro-4-[[4-(p-tolyl)piperazino]methyl...)
Affinity DataKi:  2.50E+4nM ΔG°:  -26.3kJ/mole IC50: 3.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Universite Paul Sabatier

LigandPNGBDBM43838(MLS000438679 | cid_16759689 | 4-O-[5-bromo-2-cyclo...)
Affinity DataKi:  3.00E+4nM ΔG°:  -25.8kJ/mole IC50: 3.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Universite Paul Sabatier

LigandPNGBDBM43837(CMLD004122 | methyl (4S,5R,6R)-1-(2-ethoxy-2-oxoet...)
Affinity DataKi:  7.00E+4nM ΔG°:  -23.7kJ/mole IC50: 3.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Universite Paul Sabatier

LigandPNGBDBM43829(SMR000154737 | MLS000568543 | [4-(2-hydroxyphenyl)...)
Affinity DataKi:  1.00E+5nM ΔG°:  -22.8kJ/mole IC50: 6.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Universite Paul Sabatier

LigandPNGBDBM43836(MLS000580208 | N-(2,5-dimethoxyphenyl)-2-(quinolin...)
Affinity DataKi:  1.00E+5nM ΔG°:  -22.8kJ/mole IC50: 4.00E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Universite Paul Sabatier

LigandPNGBDBM43830(5-(amoxymethyl)-3-[2-[(4-phenylthiazol-2-yl)hydraz...)
Affinity DataKi:  1.05E+5nM ΔG°:  -22.7kJ/mole IC50: 4.50E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Universite Paul Sabatier

LigandPNGBDBM43831(5-[(4-fluorophenyl)methyl]-4-oxo-6,7-dihydropyrazo...)
Affinity DataKi:  1.14E+5nM ΔG°:  -22.5kJ/mole IC50: 1.80E+6nMT: 2°CAssay Description:Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2011
Entry Details Article
PubMed