Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50012167
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115666({4-[4-Hydroxy-3-isopropyl-5-(4-pentyl-phenylethyny...)
Affinity DataKd:  0.520nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115669({4-[3-(4-Amino-phenylethynyl)-4-hydroxy-5-isopropy...)
Affinity DataKd:  90nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115667([4-(4-Hydroxy-3-isopropyl-5-phenylethynyl-benzyl)-...)
Affinity DataEC50:  500nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18885(JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...)
Affinity DataKd:  93nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha-1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataEC50:  2nMAssay Description:Half-maximum activation of human Thyroid hormone receptor alpha-1 (hTRalpha1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115668([4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phe...)
Affinity DataKd:  0.100nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115668([4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phe...)
Affinity DataEC50:  45nMAssay Description:Half-maximum activation of human Thyroid hormone receptor alpha-1 (hTRalpha1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115667([4-(4-Hydroxy-3-isopropyl-5-phenylethynyl-benzyl)-...)
Affinity DataKd:  37nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115666({4-[4-Hydroxy-3-isopropyl-5-(4-pentyl-phenylethyny...)
Affinity DataEC50:  380nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115668([4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phe...)
Affinity DataEC50:  7nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18884(CHEMBL112087 | JMC496635 Compound 4 | 2-(4-{[4-hyd...)
Affinity DataKd:  200nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha-1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataEC50:  2nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115669({4-[3-(4-Amino-phenylethynyl)-4-hydroxy-5-isopropy...)
Affinity DataKd:  330nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha-1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115668([4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phe...)
Affinity DataKd:  1.80nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha-1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataKd:  0.100nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18885(JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...)
Affinity DataKd:  20nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataKd:  0.100nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha-1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115667([4-(4-Hydroxy-3-isopropyl-5-phenylethynyl-benzyl)-...)
Affinity DataKd:  490nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha-1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18884(CHEMBL112087 | JMC496635 Compound 4 | 2-(4-{[4-hyd...)
Affinity DataKd:  35nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50115666({4-[4-Hydroxy-3-isopropyl-5-(4-pentyl-phenylethyny...)
Affinity DataKd:  5.20nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha-1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18885(JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...)
Affinity DataIC50: 370nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18884(CHEMBL112087 | JMC496635 Compound 4 | 2-(4-{[4-hyd...)
Affinity DataIC50: 680nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18885(JMC496635 Compound 5 | 2-[4-({4-hydroxy-3-[2-(4-ni...)
Affinity DataIC50: 950nMAssay Description:Half-maximum activation of human Thyroid hormone receptor alpha-1 (hTRalpha1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM18884(CHEMBL112087 | JMC496635 Compound 4 | 2-(4-{[4-hyd...)
Affinity DataIC50: 5.00E+3nMAssay Description:Half-maximum activation of human Thyroid hormone receptor alpha-1 (hTRalpha1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed