Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50011723
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109771(3-{4-[(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-...)
Affinity DataIC50: 3.5nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109757({2-[(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-pr...)
Affinity DataIC50: 7.20nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109765([4-(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-pro...)
Affinity DataIC50: 7.40nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109777({4-[((R)-1-{(S)-2-[(S)-1-(Benzooxazole-2-carbonyl)...)
Affinity DataIC50: 7.60nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109761(2,2-Dimethyl-propionic acid (S)-2-{2-[((S)-1-{(S)-...)
Affinity DataIC50: 8.90nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109763(4-Carboxymethoxy-benzoic acid (1-{2-[1-(benzooxazo...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109756((4-{[(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-p...)
Affinity DataIC50: 33nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109759(N-(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-prop...)
Affinity DataIC50: 66nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109775(3-(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-prop...)
Affinity DataIC50: 72nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109758(2,2-Dimethyl-propionic acid 2-{2-[2-(4-carboxymeth...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109769(2,2-Dimethyl-propionic acid 2-[2-({1-[2-(4-carboxy...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109755(2-[3-(1-{2-[1-(Benzooxazole-2-carbonyl)-2-methyl-p...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109768({4-[2-(2-{2-Methyl-1-[4-(3-methyl-butoxy)-benzooxa...)
Affinity DataIC50: 290nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109772(2,2-Dimethyl-propionic acid 2-(2-benzyloxycarbonyl...)
Affinity DataIC50: 450nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109770({2-Methyl-1-[4-(3-methyl-butoxy)-benzooxazole-2-ca...)
Affinity DataIC50: 7.80E+3nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109753([1-(4-Carbamoylmethoxy-benzooxazole-2-carbonyl)-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109754({2-Methyl-1-[4-(1-phenyl-pentyloxy)-benzooxazole-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109766([1-(4-Ethoxy-benzooxazole-2-carbonyl)-2-methyl-pro...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109767([1-(4-Hydroxy-benzooxazole-2-carbonyl)-2-methyl-pr...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109776([1-(4-Benzyloxy-benzooxazole-2-carbonyl)-2-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109762([1-(Benzooxazole-2-carbonyl)-2-methyl-propyl]-carb...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109764({2-Methyl-1-[4-(3-methyl-but-2-enyloxy)-benzooxazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109779({1-[4-(2-Dimethylamino-ethoxy)-benzooxazole-2-carb...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109773([2-(2-Benzyloxycarbonylamino-3-methyl-butyryl)-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109774([2-Methyl-1-(4-pentyloxy-benzooxazole-2-carbonyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109760({2-Methyl-1-[4-(3-trifluoromethyl-benzyloxy)-benzo...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50109778([2-(2-Benzyloxycarbonylamino-3-methyl-butyryl)-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of the human neutrophil elastase-catalyzed hydrolysis of the synthetic substrate Suc-Ala-Pro-Ala-MCAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed