Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50011714
TargetGlutamate receptor ionotropic, kainate 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109657(2-Amino-3-[3-hydroxy-4-(2-hydroxy-phenyl)-isoxazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using [3H]-kainic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109656(2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using [3H]-kainic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089901(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using [3H]-kainic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109652(2-Amino-3-[3-hydroxy-4-(3-hydroxy-phenyl)-isoxazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using [3H]-kainic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109653(2-Amino-3-[3-hydroxy-4-(4-hydroxy-phenyl)-isoxazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using [3H]-kainic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109655(2-Amino-3-(3-hydroxy-4-naphthalen-1-yl-isoxazol-5-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using [3H]-kainic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109658(2-Amino-3-(3-hydroxy-4-phenethyl-isoxazol-5-yl)-pr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using [3H]-kainic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109654(2-Amino-3-(3-hydroxy-4-pyridin-2-yl-isoxazol-5-yl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using [3H]-kainic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50098248(2-Amino-3-(3-hydroxy-4-phenyl-isoxazol-5-yl)-propi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using [3H]-kainic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109657(2-Amino-3-[3-hydroxy-4-(2-hydroxy-phenyl)-isoxazol...)
Affinity DataKi:  4.50E+4nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109656(2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...)
Affinity DataKi:  5.30E+4nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109655(2-Amino-3-(3-hydroxy-4-naphthalen-1-yl-isoxazol-5-...)
Affinity DataKi:  6.20E+4nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109653(2-Amino-3-[3-hydroxy-4-(4-hydroxy-phenyl)-isoxazol...)
Affinity DataKi:  6.50E+4nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109658(2-Amino-3-(3-hydroxy-4-phenethyl-isoxazol-5-yl)-pr...)
Affinity DataKi:  7.00E+4nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109653(2-Amino-3-[3-hydroxy-4-(4-hydroxy-phenyl)-isoxazol...)
Affinity DataKi:  7.10E+4nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109658(2-Amino-3-(3-hydroxy-4-phenethyl-isoxazol-5-yl)-pr...)
Affinity DataKi:  9.20E+4nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109655(2-Amino-3-(3-hydroxy-4-naphthalen-1-yl-isoxazol-5-...)
Affinity DataKi:  1.19E+5nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109657(2-Amino-3-[3-hydroxy-4-(2-hydroxy-phenyl)-isoxazol...)
Affinity DataKi:  1.25E+5nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50098248(2-Amino-3-(3-hydroxy-4-phenyl-isoxazol-5-yl)-propi...)
Affinity DataKi:  1.60E+5nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109654(2-Amino-3-(3-hydroxy-4-pyridin-2-yl-isoxazol-5-yl)...)
Affinity DataKi:  2.24E+5nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109652(2-Amino-3-[3-hydroxy-4-(3-hydroxy-phenyl)-isoxazol...)
Affinity DataKi:  2.26E+5nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109656(2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...)
Affinity DataKi:  2.49E+5nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089901(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataKi:  2.50E+5nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109654(2-Amino-3-(3-hydroxy-4-pyridin-2-yl-isoxazol-5-yl)...)
Affinity DataKi:  3.96E+5nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089901(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataKi:  4.90E+5nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109658(2-Amino-3-(3-hydroxy-4-phenethyl-isoxazol-5-yl)-pr...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109656(2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50098248(2-Amino-3-(3-hydroxy-4-phenyl-isoxazol-5-yl)-propi...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109657(2-Amino-3-[3-hydroxy-4-(2-hydroxy-phenyl)-isoxazol...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109654(2-Amino-3-(3-hydroxy-4-pyridin-2-yl-isoxazol-5-yl)...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089901(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109657(2-Amino-3-[3-hydroxy-4-(2-hydroxy-phenyl)-isoxazol...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109658(2-Amino-3-(3-hydroxy-4-phenethyl-isoxazol-5-yl)-pr...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089901(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109653(2-Amino-3-[3-hydroxy-4-(4-hydroxy-phenyl)-isoxazol...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109652(2-Amino-3-[3-hydroxy-4-(3-hydroxy-phenyl)-isoxazol...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109653(2-Amino-3-[3-hydroxy-4-(4-hydroxy-phenyl)-isoxazol...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109656(2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109652(2-Amino-3-[3-hydroxy-4-(3-hydroxy-phenyl)-isoxazol...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109655(2-Amino-3-(3-hydroxy-4-naphthalen-1-yl-isoxazol-5-...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50098248(2-Amino-3-(3-hydroxy-4-phenyl-isoxazol-5-yl)-propi...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109654(2-Amino-3-(3-hydroxy-4-pyridin-2-yl-isoxazol-5-yl)...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50109655(2-Amino-3-(3-hydroxy-4-naphthalen-1-yl-isoxazol-5-...)
Affinity DataKi: >1.00E+6nMAssay Description:The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed