Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50011681
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM6477(CHEMBL335025 | 4-[(4-chloro-5-methoxy-2-methylphen...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4531(CHEMBL127331 | 4-[(4-Chloro-5-methoxy-2-methylphen...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095226(6,7-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Dual specificity mitogen-activated protein kinase kinase (MEK-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109282(7,8-Dimethoxy-4-(4-phenoxy-phenylamino)-benzo[g]qu...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Dual specificity mitogen-activated protein kinase kinase (MEK-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109281(4-(2,4-Dichloro-phenylamino)-7,8-dimethoxy-benzo[g...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4492(CHEMBL101917 | 4-[(2,4-dichlorophenyl)amino]-6,7-d...)
Affinity DataIC50: 38nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM6477(CHEMBL335025 | 4-[(4-chloro-5-methoxy-2-methylphen...)
Affinity DataIC50: 210nMAssay Description:Inhibition of Src-transformed fibroblast cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109280(4-(3-Chloro-4-fluoro-phenylamino)-7,8-dimethoxy-be...)
Affinity DataIC50: 680nMAssay Description:Inhibition of EGFR overexpressing A431 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50109280(4-(3-Chloro-4-fluoro-phenylamino)-7,8-dimethoxy-be...)
Affinity DataIC50: 680nMAssay Description:Inhibition of EGFR overexpressing A431 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4456(4-(3-Chloro-4-fluorophenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of EGFR overexpressing A431 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4531(CHEMBL127331 | 4-[(4-Chloro-5-methoxy-2-methylphen...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Src-transformed fibroblast cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM4456(4-(3-Chloro-4-fluorophenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50: 5.17E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed