Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50011522
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107530(4-[4-(5-Chloro-thiophen-2-yl)-2-methyl-oxazol-5-yl...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50: 24nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107522(4-(5-Chloro-thiophen-2-yl)-5-(4-methanesulfonyl-ph...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107526(5-(4-Methanesulfonyl-phenyl)-2-methyl-4-(5-methyl-...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107527(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfo...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107519(4-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-2-methyl...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107515(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107516(5-(4-Methanesulfonyl-phenyl)-2-methyl-4-phenyl-oxa...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107529(4-(5-Ethyl-thiophen-2-yl)-5-(4-methanesulfonyl-phe...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107521(4-Cyclohexyl-2-ethyl-5-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 270nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107514(4-Cycloheptyl-5-(4-methanesulfonyl-phenyl)-2-methy...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107530(4-[4-(5-Chloro-thiophen-2-yl)-2-methyl-oxazol-5-yl...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107524(5-(5-Chloro-thiophen-2-yl)-4-(4-methanesulfonyl-ph...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107518(5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107517(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-N-methyl-ben...)
Affinity DataIC50: 3.10E+3nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50: 4.70E+3nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107522(4-(5-Chloro-thiophen-2-yl)-5-(4-methanesulfonyl-ph...)
Affinity DataIC50: 1.25E+4nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107523(4-Cyclopentyl-5-(4-methanesulfonyl-phenyl)-2-methy...)
Affinity DataIC50: 1.80E+4nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107525(5-(4-Ethanesulfonyl-phenyl)-4-(4-fluoro-phenyl)-2-...)
Affinity DataIC50: 3.80E+4nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107515(4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 4.20E+4nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107527(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfo...)
Affinity DataIC50: 4.75E+4nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107526(5-(4-Methanesulfonyl-phenyl)-2-methyl-4-(5-methyl-...)
Affinity DataIC50: 4.75E+4nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107521(4-Cyclohexyl-2-ethyl-5-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 6.00E+4nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107524(5-(5-Chloro-thiophen-2-yl)-4-(4-methanesulfonyl-ph...)
Affinity DataIC50: 9.30E+4nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107520(4-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-2-phenyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107523(4-Cyclopentyl-5-(4-methanesulfonyl-phenyl)-2-methy...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107517(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-N-methyl-ben...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107514(4-Cycloheptyl-5-(4-methanesulfonyl-phenyl)-2-methy...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107529(4-(5-Ethyl-thiophen-2-yl)-5-(4-methanesulfonyl-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107520(4-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-2-phenyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity towards human recombinant Prostaglandin G/H synthase 2 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107518(5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107525(5-(4-Ethanesulfonyl-phenyl)-4-(4-fluoro-phenyl)-2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107519(4-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-2-methyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107516(5-(4-Methanesulfonyl-phenyl)-2-methyl-4-phenyl-oxa...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity towards human platelet recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed