Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50035171
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105448(2-Amino-N-hydroxy-3-(4-phenoxy-benzenesulfonyl)-2-...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105459(N-Hydroxy-2-methyl-3-(4-phenoxy-benzenesulfonyl)-2...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105457(2-Amino-N-hydroxy-2-methyl-3-(4-phenoxy-benzenesul...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105456(2-Benzylamino-N-hydroxy-2-methyl-3-(4-phenoxy-benz...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105456(2-Benzylamino-N-hydroxy-2-methyl-3-(4-phenoxy-benz...)
Affinity DataIC50: 0.300nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105451(N-Hydroxy-2-methyl-2-[(naphthalen-2-ylmethyl)-amin...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105448(2-Amino-N-hydroxy-3-(4-phenoxy-benzenesulfonyl)-2-...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105453(2-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-N-hydroxy-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105457(2-Amino-N-hydroxy-2-methyl-3-(4-phenoxy-benzenesul...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105459(N-Hydroxy-2-methyl-3-(4-phenoxy-benzenesulfonyl)-2...)
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 0.75nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105453(2-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-N-hydroxy-...)
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105458(N-Hydroxy-2-methyl-2-phenethylamino-3-(4-phenoxy-b...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105455(2-Ethylamino-N-hydroxy-2-methyl-3-(4-phenoxy-benze...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105451(N-Hydroxy-2-methyl-2-[(naphthalen-2-ylmethyl)-amin...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105455(2-Ethylamino-N-hydroxy-2-methyl-3-(4-phenoxy-benze...)
Affinity DataIC50: 1.60nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105458(N-Hydroxy-2-methyl-2-phenethylamino-3-(4-phenoxy-b...)
Affinity DataIC50: 2.40nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105447(2-Amino-N-hydroxy-2-methyl-3-(4-phenylsulfanyl-ben...)
Affinity DataIC50: 2.40nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 2.90nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105447(2-Amino-N-hydroxy-2-methyl-3-(4-phenylsulfanyl-ben...)
Affinity DataIC50: 3.20nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 4.60nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105461(2-Dimethylamino-N-hydroxy-2-methyl-3-(4-phenoxy-be...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 5.10nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105461(2-Dimethylamino-N-hydroxy-2-methyl-3-(4-phenoxy-be...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105460(2-Acetylamino-N-hydroxy-2-methyl-3-(4-phenoxy-benz...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105460(2-Acetylamino-N-hydroxy-2-methyl-3-(4-phenoxy-benz...)
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105452(N-Hydroxy-2-methyl-3-(4-phenoxy-benzenesulfonyl)-2...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105448(2-Amino-N-hydroxy-3-(4-phenoxy-benzenesulfonyl)-2-...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105452(N-Hydroxy-2-methyl-3-(4-phenoxy-benzenesulfonyl)-2...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105449(N-[1-Hydroxycarbamoyl-2-(4-phenoxy-benzenesulfonyl...)
Affinity DataIC50: 161nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105457(2-Amino-N-hydroxy-2-methyl-3-(4-phenoxy-benzenesul...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105449(N-[1-Hydroxycarbamoyl-2-(4-phenoxy-benzenesulfonyl...)
Affinity DataIC50: 184nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105450(2-(4-Phenoxy-benzenesulfonylmethyl)-1-prop-2-ynyl-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105454(2-Acetylamino-N-hydroxy-2-methyl-3-(4-phenylsulfan...)
Affinity DataIC50: 540nMAssay Description:Inhibitory activity against human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105454(2-Acetylamino-N-hydroxy-2-methyl-3-(4-phenylsulfan...)
Affinity DataIC50: 580nMAssay Description:Inhibitory activity against human Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105459(N-Hydroxy-2-methyl-3-(4-phenoxy-benzenesulfonyl)-2...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105456(2-Benzylamino-N-hydroxy-2-methyl-3-(4-phenoxy-benz...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105455(2-Ethylamino-N-hydroxy-2-methyl-3-(4-phenoxy-benze...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105453(2-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-N-hydroxy-...)
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105458(N-Hydroxy-2-methyl-2-phenethylamino-3-(4-phenoxy-b...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50105447(2-Amino-N-hydroxy-2-methyl-3-(4-phenylsulfanyl-ben...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibitory activity against human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
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