Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50011274
TargetPeptide deformylase, mitochondrial(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 7nMAssay Description:Antibacterial activity against Escherichia coli Peptide deformylase. NiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase, mitochondrial(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089194(CHEMBL308333 | N*4*-Hydroxy-N*1*-[1-(2-hydroxymeth...)
Affinity DataIC50: 10nMAssay Description:Antibacterial activity against Escherichia coli Peptide deformylase. NiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase, mitochondrial(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104500(2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid (1...)
Affinity DataIC50: 70nMAssay Description:Antibacterial activity against Escherichia coli Peptide deformylase. NiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089194(CHEMBL308333 | N*4*-Hydroxy-N*1*-[1-(2-hydroxymeth...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089194(CHEMBL308333 | N*4*-Hydroxy-N*1*-[1-(2-hydroxymeth...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089194(CHEMBL308333 | N*4*-Hydroxy-N*1*-[1-(2-hydroxymeth...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089194(CHEMBL308333 | N*4*-Hydroxy-N*1*-[1-(2-hydroxymeth...)
Affinity DataIC50: 6.70E+3nMAssay Description:The compound was evaluated in vitro for the inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compound was evaluated in vitro for the inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104500(2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid (1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104500(2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid (1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104500(2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid (1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104500(2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid (1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50089194(CHEMBL308333 | N*4*-Hydroxy-N*1*-[1-(2-hydroxymeth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed