Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50011164
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50063920(Ro-31-9790 | (R)-N*1*-((S)-2,2-Dimethyl-1-methylca...)
Affinity DataKi:  2nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50063920(Ro-31-9790 | (R)-N*1*-((S)-2,2-Dimethyl-1-methylca...)
Affinity DataKi:  2nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103099((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  11nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103097((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  16nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103097((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  16nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103102((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  17nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103096((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  17nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103092((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  17nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103098((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  20nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103093((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  20nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103092((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  21nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103099((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  24nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103098((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  27nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103102((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  27nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103097((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  28nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103093((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  29nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103095((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  29nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103101((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  31nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103100((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  33nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103098((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  34nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103102((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  36nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103101((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  38nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103093((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  41nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103099((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  42nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103099((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  45nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103095((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  47nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103096((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  55nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103101((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  55nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103094((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  64nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103101((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  73nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103096((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  80nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50063920(Ro-31-9790 | (R)-N*1*-((S)-2,2-Dimethyl-1-methylca...)
Affinity DataKi:  87nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103095((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  89nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103093((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  93nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103096((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  97nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103094((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  98nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103102((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  120nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103097((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  135nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103092((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  142nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103095((2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentan...)
Affinity DataKi:  153nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50103100((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  156nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103094((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  170nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103100((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  181nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50063920(Ro-31-9790 | (R)-N*1*-((S)-2,2-Dimethyl-1-methylca...)
Affinity DataKi:  310nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103094((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  354nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103100((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  406nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103098((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  437nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50103092((R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methy...)
Affinity DataKi:  2.32E+3nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed