Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50011163
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103087([4-((R)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  0.800nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103078([4-(4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phe...)
Affinity DataKi:  1nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103083((4-{(S)-4-[(S)-1-(4-Benzo[1,3]dioxol-5-ylmethyl-ph...)
Affinity DataKi:  18nMAssay Description:Inhibition of [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103088([4-((S)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  28nMAssay Description:Inhibition of [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103091((4-{4-[4-(Benzo[1,3]dioxole-5-sulfonyl)-benzyl]-pi...)
Affinity DataKi:  31nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103080((2-Amino-6-methyl-phenyl)-[4-((S)-4-{(S)-1-[4-(ben...)
Affinity DataKi:  31nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to C-C chemokine receptor type 5 expressed in membrane preparation of CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103085((2-Amino-6-chloro-phenyl)-[4-((S)-4-{(S)-1-[4-(ben...)
Affinity DataKi:  32nMAssay Description:Inhibition of [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103090((4-{(S)-4-[(S)-1-(4-Benzo[1,3]dioxol-5-ylmethyl-ph...)
Affinity DataKi:  35nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103084({4-[(S)-4-(4-Benzo[1,3]dioxol-5-ylmethyl-benzyl)-3...)
Affinity DataKi: >40nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103089((4-{(S)-4-[4-(Benzo[1,3]dioxole-5-sulfonyl)-benzyl...)
Affinity DataKi: >40nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103084({4-[(S)-4-(4-Benzo[1,3]dioxol-5-ylmethyl-benzyl)-3...)
Affinity DataKi:  44nMAssay Description:Inhibition of [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103086([4-((S)-4-{(S)-1-[4-(3-Chloro-benzyl)-phenyl]-ethy...)
Affinity DataKi:  45nMAssay Description:Inhibition of [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103079([4-((S)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  49nMAssay Description:Inhibition of [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103089((4-{(S)-4-[4-(Benzo[1,3]dioxole-5-sulfonyl)-benzyl...)
Affinity DataKi:  74nMAssay Description:Inhibition of [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103090((4-{(S)-4-[(S)-1-(4-Benzo[1,3]dioxol-5-ylmethyl-ph...)
Affinity DataIC50: 90nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103080((2-Amino-6-methyl-phenyl)-[4-((S)-4-{(S)-1-[4-(ben...)
Affinity DataKi:  100nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103085((2-Amino-6-chloro-phenyl)-[4-((S)-4-{(S)-1-[4-(ben...)
Affinity DataKi:  100nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103082([4-((S)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  230nMAssay Description:Inhibition of [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103079([4-((S)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  270nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103082([4-((S)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  352nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103081({4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-benzyl)-piper...)
Affinity DataKi:  352nMAssay Description:Inhibition of [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103087([4-((R)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataIC50: 440nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103078([4-(4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phe...)
Affinity DataKi:  442nMAssay Description:Inhibition of [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103088([4-((S)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)...)
Affinity DataKi:  485nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103081({4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-benzyl)-piper...)
Affinity DataKi:  497nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103083((4-{(S)-4-[(S)-1-(4-Benzo[1,3]dioxol-5-ylmethyl-ph...)
Affinity DataKi:  760nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103091((4-{4-[4-(Benzo[1,3]dioxole-5-sulfonyl)-benzyl]-pi...)
Affinity DataKi: >1.30E+3nMAssay Description:Inhibition of [125I]-labeled RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50103086([4-((S)-4-{(S)-1-[4-(3-Chloro-benzyl)-phenyl]-ethy...)
Affinity DataKi: >1.40E+3nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed