Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50011096
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM17659(pentanedioic acid analogue, (RS)-1 | 2-(phosphonom...)
Affinity DataIC50: 5.10nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102256(2-[3-(1-Carboxy-2-mercapto-ethyl)-ureido]-pentaned...)
Affinity DataIC50: 6.90nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102259(2-[(2,4-Dicarboxy-butyl)-hydroxy-phosphinoylmethyl...)
Affinity DataIC50: 21.7nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102255(2-[3-(2-tert-Butylsulfanyl-1-carboxy-ethyl)-ureido...)
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102257(2-[3-(1,2-Dicarboxy-ethyl)-ureido]-pentanedioic ac...)
Affinity DataIC50: 46.1nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase IIusing a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102258((S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-ureido]-...)
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102260(Glu-Glu | 2-(2-Amino-4-carboxy-butyrylamino)-penta...)
Affinity DataIC50: 750nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102262(2-(2-Amino-3-carboxy-propionylamino)-pentanedioic ...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase IIusing a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102261(2-[3-(1,2-Dicarboxy-ethyl)-ureido]-succinic acid |...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase IIusing a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed