Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50011012
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101257BDBM50101257((1R,2S,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymet...)
Affinity DataKi:  0.430nMAssay Description:Tested for in vitro inhibition of [125I]ET1 binding to CHO cells expressing human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101268BDBM50101268([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymetho...)
Affinity DataIC50: 4.10nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101258BDBM50101258([(1R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymetho...)
Affinity DataIC50: 5.40nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101271BDBM50101271([(1R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymetho...)
Affinity DataIC50: 6.10nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101259BDBM50101259([(1R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymetho...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101262BDBM50101262(3-[2-((1R,3R)-3-Benzo[1,3]dioxol-5-yl-2-carboxymet...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101257BDBM50101257((1R,2S,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymet...)
Affinity DataKi:  15nMAssay Description:Inhibition of [125I]-ET-1 binding to CHO cells expressing human Endothelin B receptor at a concentration of 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101275BDBM50101275(4-[2-((1S,3R)-3-Benzo[1,3]dioxol-5-yl-2-carboxymet...)
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101261BDBM50101261({(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-[4-met...)
Affinity DataIC50: 29nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101249BDBM50101249({2-[(1S,3R)-3-Benzo[1,3]dioxol-5-yl-6-ethoxy-2-(1H...)
Affinity DataIC50: 31nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101274BDBM50101274([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(2-hyd...)
Affinity DataIC50: 58nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101254BDBM50101254([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(3,4,5...)
Affinity DataIC50: 66nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101250BDBM50101250(3-[2-((1S,3R)-3-Benzo[1,3]dioxol-5-yl-2-carboxymet...)
Affinity DataIC50: 68nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101247BDBM50101247([(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(2-hyd...)
Affinity DataIC50: 77nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101251BDBM50101251([(1R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymetho...)
Affinity DataIC50: 85nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101260BDBM50101260([(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(4-met...)
Affinity DataIC50: 95nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101264BDBM50101264([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymetho...)
Affinity DataIC50: 96nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101263BDBM50101263([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(4-met...)
Affinity DataIC50: 96nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101253BDBM50101253([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymetho...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101269BDBM50101269([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-phen...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101255BDBM50101255([(1R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymetho...)
Affinity DataIC50: 310nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101273BDBM50101273([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymetho...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101272BDBM50101272({(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-[4-met...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101267BDBM50101267([(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(3,4,5...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101248BDBM50101248([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-methoxy-3-(4-me...)
Affinity DataIC50: 3.30E+3nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101252BDBM50101252([(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymetho...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101270BDBM50101270([(1S,3S)-1-(2-Carboxymethoxy-4-methoxy-phenyl)-3-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101266BDBM50101266([(1S,3R)-1-(2-Carboxymethoxy-4-methoxy-phenyl)-3-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101265BDBM50101265({(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-[2-(2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101256BDBM50101256((1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-2-(1H-tet...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed