Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50010866
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099466((R)-1-[4-(Naphthalen-2-yloxy)-benzyl]-2-oxo-imidaz...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50: 28nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099466((R)-1-[4-(Naphthalen-2-yloxy)-benzyl]-2-oxo-imidaz...)
Affinity DataIC50: 56nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099466((R)-1-[4-(Naphthalen-2-yloxy)-benzyl]-2-oxo-imidaz...)
Affinity DataIC50: 59nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50: 62nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 82nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099469((4R)-1-[4-(benzyloxy)benzyl]-N-hydroxy-2-oxoimidaz...)
Affinity DataIC50: 123nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089187(4-(4'-Fluoro-biphenyl-4-yl)-5-oxo-pyrrolidine-2-ca...)
Affinity DataIC50: 182nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099467((4R)-1-[3-(4-fluorophenoxy)benzyl]-N-hydroxy-2-oxo...)
Affinity DataIC50: 214nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099464((R)-1-(4-Methoxy-benzyl)-2-oxo-imidazolidine-4-car...)
Affinity DataIC50: 281nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099470((R)-1-(4'-Fluoro-biphenyl-4-ylmethyl)-2-oxo-imidaz...)
Affinity DataIC50: 331nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099464((R)-1-(4-Methoxy-benzyl)-2-oxo-imidazolidine-4-car...)
Affinity DataIC50: 388nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099468((4R)-N-hydroxy-1-[4-(1-naphthyloxy)benzyl]-2-oxoim...)
Affinity DataIC50: 825nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099466((R)-1-[4-(Naphthalen-2-yloxy)-benzyl]-2-oxo-imidaz...)
Affinity DataIC50: 940nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089185((2R,4S)-4-[4-(benzyloxy)phenyl]-N-hydroxy-5-oxopyr...)
Affinity DataIC50: 946nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089188(4-(4-Methoxy-phenyl)-5-oxo-pyrrolidine-2-carboxyli...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182(4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrrolidine-...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099463((4R)-N-hydroxy-1-(2-naphthylmethyl)-2-oxoimidazoli...)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089186((2R,4S)-N-hydroxy-4-(2-naphthyl)-5-oxopyrrolidine-...)
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099471((2R,4S)-4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy-5-...)
Affinity DataIC50: 4.76E+3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50: 5.45E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089187(4-(4'-Fluoro-biphenyl-4-yl)-5-oxo-pyrrolidine-2-ca...)
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099468((4R)-N-hydroxy-1-[4-(1-naphthyloxy)benzyl]-2-oxoim...)
Affinity DataIC50: 8.02E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089188(4-(4-Methoxy-phenyl)-5-oxo-pyrrolidine-2-carboxyli...)
Affinity DataIC50: 8.04E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099466((R)-1-[4-(Naphthalen-2-yloxy)-benzyl]-2-oxo-imidaz...)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099470((R)-1-(4'-Fluoro-biphenyl-4-ylmethyl)-2-oxo-imidaz...)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099469((4R)-1-[4-(benzyloxy)benzyl]-N-hydroxy-2-oxoimidaz...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099471((2R,4S)-4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy-5-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089186((2R,4S)-N-hydroxy-4-(2-naphthyl)-5-oxopyrrolidine-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099463((4R)-N-hydroxy-1-(2-naphthylmethyl)-2-oxoimidazoli...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089185((2R,4S)-4-[4-(benzyloxy)phenyl]-N-hydroxy-5-oxopyr...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099467((4R)-1-[3-(4-fluorophenoxy)benzyl]-N-hydroxy-2-oxo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed