Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50010830
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099184((2S,5R,6R)-6-[1-(4-Amino-phenyl)-1H-[1,2,3]triazol...)
Affinity DataIC50: 600nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099190((2S,5R,6R)-6-[1-(4-Hydroxy-phenyl)-1H-[1,2,3]triaz...)
Affinity DataIC50: 700nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099192((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-phenyl-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50021954(UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099186((2S,5S)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099184((2S,5R,6R)-6-[1-(4-Amino-phenyl)-1H-[1,2,3]triazol...)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099193((2S,5R,6R)-6-[1-(4-Fluoro-phenyl)-1H-[1,2,3]triazo...)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099184((2S,5R,6R)-6-[1-(4-Amino-phenyl)-1H-[1,2,3]triazol...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099190((2S,5R,6R)-6-[1-(4-Hydroxy-phenyl)-1H-[1,2,3]triaz...)
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099190((2S,5R,6R)-6-[1-(4-Hydroxy-phenyl)-1H-[1,2,3]triaz...)
Affinity DataIC50: 2.30E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099186((2S,5S)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099193((2S,5R,6R)-6-[1-(4-Fluoro-phenyl)-1H-[1,2,3]triazo...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099188((2S,5S)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099191((2S,5S)-6-((E)-3-Cyano-allyl)-3,3-dimethyl-4,4,7-t...)
Affinity DataIC50: 3.10E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099192((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-phenyl-1...)
Affinity DataIC50: 3.40E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099193((2S,5R,6R)-6-[1-(4-Fluoro-phenyl)-1H-[1,2,3]triazo...)
Affinity DataIC50: 4.10E+3nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099185((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-pyrrolid...)
Affinity DataIC50: 5.20E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099188((2S,5S)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50: 6.50E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099194((2S,5R,6R)-6-{1-[2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50: 6.60E+3nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099185((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-pyrrolid...)
Affinity DataIC50: 7.90E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099195((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50: 8.40E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099189((2S,5R)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50: 8.60E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099187((2S,5R)-6-[(E)-3-(Methoxy-methyl-carbamoyl)-allyl]...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099196((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-but...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099194((2S,5R,6R)-6-{1-[2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099196((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-but...)
Affinity DataIC50: 1.70E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099187((2S,5R)-6-[(E)-3-(Methoxy-methyl-carbamoyl)-allyl]...)
Affinity DataIC50: 1.70E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099185((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-pyrrolid...)
Affinity DataIC50: 2.20E+4nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099194((2S,5R,6R)-6-{1-[2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50: 2.40E+4nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099191((2S,5S)-6-((E)-3-Cyano-allyl)-3,3-dimethyl-4,4,7-t...)
Affinity DataIC50: 2.40E+4nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099189((2S,5R)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50: 2.90E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099188((2S,5S)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50: 4.80E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099186((2S,5S)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50: 6.40E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50021954(UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...)
Affinity DataIC50: 6.60E+4nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099195((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50: 7.10E+4nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099195((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099189((2S,5R)-6-((E)-3-Methoxycarbonyl-allyl)-3,3-dimeth...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099196((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-but...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50021954(UNASYN | 3,3-Dimethyl-4,4,7-trioxo-4lambda*6*-thia...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099191((2S,5S)-6-((E)-3-Cyano-allyl)-3,3-dimethyl-4,4,7-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099192((2S,5R,6R)-3,3-Dimethyl-4,4,7-trioxo-6-(1-phenyl-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099187((2S,5R)-6-[(E)-3-(Methoxy-methyl-carbamoyl)-allyl]...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed