Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50010758
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098391(4-(2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5...)
Affinity DataIC50: 0.440nMAssay Description:In vitro inhibition of binding to GnRH receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098391(4-(2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of gonadotropin-releasing hormone receptor in rhesus monkeyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098391(4-(2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5...)
Affinity DataIC50: 1nMAssay Description:Functional antagonism at the human GnRH receptor (PI turnover)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098391(4-(2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of binding to GnRH receptor in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098391(4-(2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5...)
Affinity DataIC50: 7nMAssay Description:Functional antagonism at the rhesus monkey gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098391(4-(2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of binding to gonadotropin-releasing hormone receptor in dogMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098391(4-(2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5...)
Affinity DataIC50: 81nMAssay Description:Functional antagonism at GnRH receptor in rat (PI turnover)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50098391(4-(2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5...)
Affinity DataIC50: 350nMAssay Description:Functional antagonism at gonadotropin-releasing hormone receptor in dog (PI turnover)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed