Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50010660
Target5-hydroxytryptamine receptor 1A(Rat)
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097342(3-Chloro-4-[4-(3',6'-dihydro-2'H-[2,4']bipyridinyl...)
Affinity DataIC50: 0.470nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097341(3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...)
Affinity DataIC50: 0.770nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097343(3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097345(3-Methyl-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 10nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 11nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097344(4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-4H-b...)
Affinity DataIC50: 18nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097341(3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...)
Affinity DataIC50: 51nMAssay Description:Binding affinity to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50001859(BUSPAR | CHEMBL49 | 8-[4-(4-Pyrimidin-2-yl-piperaz...)
Affinity DataIC50: 55nMAssay Description:Binding affinity to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097342(3-Chloro-4-[4-(3',6'-dihydro-2'H-[2,4']bipyridinyl...)
Affinity DataIC50: 84nMAssay Description:Binding affinity to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097343(3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 199nMAssay Description:Binding affinity to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097345(3-Methyl-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed