Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50010611
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087036(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]ac...)
Affinity DataKi:  6.90nMAssay Description:In vitro binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096742((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2,7-diaza-benz...)
Affinity DataKi:  27nMAssay Description:In vitro binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096741((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-1,7-diaza-benz...)
Affinity DataKi:  34nMAssay Description:In vitro binding affinity towards cloned human 5-hydroxytryptamine 1A receptor expressed in Chinese hamster ovary (CHO) cells using [3H]8-OH-DPAT as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087036(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]ac...)
Affinity DataKi:  41nMAssay Description:In vitro binding affinity towards cloned human 5-hydroxytryptamine 1A receptor expressed in Chinese hamster ovary (CHO) cells using [3H]8-OH-DPAT as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM29644(APOMORPHINE HYDROCHLORIDE | SMR000059235 | APOMORP...)
Affinity DataKi:  42nMAssay Description:In vitro binding affinity towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202333((R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-b...)
Affinity DataKi:  55nMAssay Description:In vitro binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202333((R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-b...)
Affinity DataKi:  55nMAssay Description:In vitro binding affinity towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096742((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2,7-diaza-benz...)
Affinity DataKi:  62nMAssay Description:In vitro binding affinity towards cloned human 5-hydroxytryptamine 1A receptor expressed in Chinese hamster ovary (CHO) cells using [3H]8-OH-DPAT as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096741((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-1,7-diaza-benz...)
Affinity DataKi:  81nMAssay Description:In vitro binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50087036(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]ac...)
Affinity DataKi:  83nMAssay Description:In vitro binding affinity towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202333((R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-b...)
Affinity DataKi:  178nMAssay Description:In vitro binding affinity towards cloned human 5-hydroxytryptamine 1A receptor expressed in Chinese hamster ovary (CHO) cells using [3H]8-OH-DPAT as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM29644(APOMORPHINE HYDROCHLORIDE | SMR000059235 | APOMORP...)
Affinity DataKi:  188nMAssay Description:In vitro binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096739((R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-be...)
Affinity DataKi:  265nMAssay Description:In vitro binding affinity towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096740((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-be...)
Affinity DataKi:  283nMAssay Description:In vitro binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM29644(APOMORPHINE HYDROCHLORIDE | SMR000059235 | APOMORP...)
Affinity DataKi:  296nMAssay Description:In vitro binding affinity towards cloned human 5-hydroxytryptamine 1A receptor expressed in Chinese hamster ovary (CHO) cells using [3H]8-OH-DPAT as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096741((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-1,7-diaza-benz...)
Affinity DataKi:  327nMAssay Description:In vitro binding affinity towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202298((R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benz...)
Affinity DataKi:  341nMAssay Description:In vitro binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202298((R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benz...)
Affinity DataKi:  373nMAssay Description:In vitro binding affinity towards cloned human 5-hydroxytryptamine 1A receptor expressed in Chinese hamster ovary (CHO) cells using [3H]8-OH-DPAT as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096740((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-be...)
Affinity DataKi:  541nMAssay Description:In vitro binding affinity towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096740((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-be...)
Affinity DataKi:  1.15E+3nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in rat hippocampus membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096742((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2,7-diaza-benz...)
Affinity DataKi:  1.33E+3nMAssay Description:In vitro binding affinity towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096739((R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-be...)
Affinity DataKi:  1.48E+3nMAssay Description:In vitro binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096739((R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-be...)
Affinity DataKi:  2.03E+3nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in rat hippocampus membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50202298((R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benz...)
Affinity DataKi:  6.11E+3nMAssay Description:In vitro binding affinity towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed