Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50010573
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096393(Benzo[b]thiophene-2-carboxylic acid [(S)-3-methyl-...)
Affinity DataKi:  7nMAssay Description:Inhibitory activity was evaluated against cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096392((S)-2-[2-(3,4-Dimethoxy-phenyl)-acetylamino]-4-met...)
Affinity DataKi:  10nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096392((S)-2-[2-(3,4-Dimethoxy-phenyl)-acetylamino]-4-met...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity was evaluated against cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096383(Benzo[b]thiophene-2-carboxylic acid [(S)-3-methyl-...)
Affinity DataKi:  11nMAssay Description:Inhibitory activity was evaluated against cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096397(Naphthalene-2-carboxylic acid [(S)-3-methyl-1-((S)...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity was evaluated against cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096396(Quinoline-2-carboxylic acid [(S)-3-methyl-1-((S)-4...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity was evaluated against cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096398(Naphthalene-2-carboxylic acid [(S)-3-methyl-1-(3-o...)
Affinity DataKi:  32nMAssay Description:Inhibitory activity was evaluated against cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096398(Naphthalene-2-carboxylic acid [(S)-3-methyl-1-(3-o...)
Affinity DataKi:  32nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19797(CHEMBL301683 | benzyl N-[(1S)-1-{[(2S)-4-methoxy-3...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity was evaluated against cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096394(Benzo[b]thiophene-2-carboxylic acid [(R)-3-methyl-...)
Affinity DataKi:  68nMAssay Description:Inhibitory activity was evaluated against cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19815((2S)-2-(1-benzothiophen-2-ylformamido)-4-methyl-N-...)
Affinity DataKi:  70nMAssay Description:Inhibition of cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19815((2S)-2-(1-benzothiophen-2-ylformamido)-4-methyl-N-...)
Affinity DataKi:  70nMAssay Description:Inhibitory activity was evaluated against cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096395(Naphthalene-2-carboxylic acid [(R)-3-methyl-1-((R)...)
Affinity DataKi:  470nMAssay Description:Inhibitory activity was evaluated against cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50096399(Quinoline-2-carboxylic acid [(R)-3-methyl-1-((R)-4...)
Affinity DataKi:  590nMAssay Description:Inhibitory activity was evaluated against cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed