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Found
32
Enz. Inhib. hit(s) with all data for entry = 5295
Target
D(2) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
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Affinity Data
Ki: 0.380nM
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 0.530nM
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Date in BDB:
4/25/2012
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Target
D(2) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50005118
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
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Affinity Data
Ki: 1nM
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Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Affinity Data
Ki: 1.20nM
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(3) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Ki: 1.20nM
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Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 1.30nM
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(3) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
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Affinity Data
Ki: 1.60nM
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PC cid
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(3) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50005118
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
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Affinity Data
Ki: 1.80nM
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Date in BDB:
4/25/2012
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PubMed
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Target
D(4) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 2.30nM
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PC cid
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(3) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
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Affinity Data
Ki: 2.30nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM11638
(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
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Affinity Data
Ki: 2.5nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(3) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
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Affinity Data
Ki: 2.70nM
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ChEBI
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PC cid
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(3) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 6.70nM
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PC cid
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(4) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.5nM
More data for this Ligand-Target Pair
Target Info
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PC cid
PC sid
PDB
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In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Ki: 7.5nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
PC cid
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(3) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM11638
(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
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Affinity Data
Ki: 8nM
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ChEBI
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PC cid
PC sid
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In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
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Target
D(4) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50001888
([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
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Affinity Data
Ki: 9.70nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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KEGG
PC cid
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In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
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Target
D(4) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50002338
(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Copy SMILES
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Affinity Data
Ki: 10nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
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Target
D(4) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
Copy SMILES
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Affinity Data
Ki: 10.1nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
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Target
D(4) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Affinity Data
Ki: 15nM
More data for this Ligand-Target Pair
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ChEBI
PC cid
PC sid
Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(4) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Affinity Data
Ki: 22nM
More data for this Ligand-Target Pair
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ChEBI
PC cid
PC sid
Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Copy SMILES
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Affinity Data
Ki: 35nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
PC cid
PC sid
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(3) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
Copy SMILES
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Affinity Data
Ki: 49nM
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ChEBI
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PC sid
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In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50026045
(CHEMBL22242 | 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-...)
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Affinity Data
Ki: 54nM
More data for this Ligand-Target Pair
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ChEBI
CHEMBL
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PC cid
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In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
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Target
D(3) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 83nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
PC cid
PC sid
Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50095890
(2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-...)
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Affinity Data
Ki: 105nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
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PC cid
PC sid
Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(3) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50095890
(2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-...)
Copy SMILES
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Affinity Data
Ki: 340nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(3) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50026045
(CHEMBL22242 | 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-...)
Copy SMILES
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Affinity Data
Ki: 969nM
More data for this Ligand-Target Pair
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ChEBI
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PC cid
PC sid
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In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
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Target
D(4) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50095890
(2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.00E+3nM
More data for this Ligand-Target Pair
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ChEBI
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DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(4) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50005118
(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Copy SMILES
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Affinity Data
Ki: 2.40E+3nM
More data for this Ligand-Target Pair
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ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
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PubMed
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Target
D(4) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM50026045
(CHEMBL22242 | 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-...)
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Affinity Data
Ki: 2.80E+3nM
More data for this Ligand-Target Pair
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PC cid
PC sid
Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
Copy Entry DOI
PubMed
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Target
D(4) dopamine receptor
(Rat)
University of Reading
Curated by
PDSP K
i
Database
Ligand
BDBM11638
(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
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Affinity Data
Ki: >1.00E+4nM
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Date in BDB:
4/25/2012
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