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Found
125
Enz. Inhib. hit(s) with all data for entry = 5290
Target
Histamine H1 receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Affinity Data
Ki: 0.0870nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
PC cid
PC sid
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
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Affinity Data
Ki: 0.120nM
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Date in BDB:
4/25/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
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Affinity Data
Ki: 0.140nM
More data for this Ligand-Target Pair
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Date in BDB:
4/25/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Affinity Data
Ki: 0.150nM
More data for this Ligand-Target Pair
Target Info
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Date in BDB:
4/25/2012
Entry Details
Article
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Target
Muscarinic acetylcholine receptor M2
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM81768
(BENZYLIC ACID | NSC_5311391 | CAS_6581-06-2 | Quin...)
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Affinity Data
Ki: 0.170nM
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50034043
(CHEMBL14376 | 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazo...)
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Affinity Data
Ki: 0.200nM
More data for this Ligand-Target Pair
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Date in BDB:
4/25/2012
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Article
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM84994
(NSC_163091 | CAS_163091 | ORG-5222)
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Affinity Data
Ki: 0.270nM
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Date in BDB:
4/25/2012
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Article
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PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM29568
([3H]-Minipress | [3H]-Furazosin | PRAZOSIN HYDROCH...)
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Affinity Data
Ki: 0.280nM
More data for this Ligand-Target Pair
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Date in BDB:
4/25/2012
Entry Details
Article
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PubMed
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Target
D(2) dopamine receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Affinity Data
Ki: 0.280nM
More data for this Ligand-Target Pair
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ChEBI
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Date in BDB:
4/25/2012
Entry Details
Article
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PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50034043
(CHEMBL14376 | 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazo...)
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Affinity Data
Ki: 0.310nM
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 1D
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Affinity Data
Ki: 0.320nM
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CHEMBL
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Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM84994
(NSC_163091 | CAS_163091 | ORG-5222)
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Affinity Data
Ki: 0.770nM
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Target Info
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
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Affinity Data
Ki: 0.900nM
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Target Info
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Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM84994
(NSC_163091 | CAS_163091 | ORG-5222)
Copy SMILES
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Affinity Data
Ki: 1.10nM
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Target Info
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ChEBI
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50252513
(9-OH-risperidone | Invega | CHEMBL1621 | 9-hydroxy...)
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Affinity Data
Ki: 1.21nM
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In Depth
Date in BDB:
4/25/2012
Entry Details
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Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Affinity Data
Ki: 1.48nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
PC cid
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Copy SMILES
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Affinity Data
Ki: 1.90nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM84994
(NSC_163091 | CAS_163091 | ORG-5222)
Copy SMILES
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Affinity Data
Ki: 2nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
5-hydroxytryptamine receptor 1D
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Copy SMILES
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Affinity Data
Ki: 2.40nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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PDB
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Affinity Data
Ki: 2.5nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
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PubMed
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Target
Histamine H1 receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM22567
(CHEMBL511 | PYRILAMINE | 3H]pyrilamine | N-[2-(dim...)
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Affinity Data
Ki: 2.5nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Affinity Data
Ki: 2.59nM
More data for this Ligand-Target Pair
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ChEBI
PC cid
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
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PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM21395
(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
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Affinity Data
Ki: 2.60nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2A
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM35255
(2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...)
Copy SMILES
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Affinity Data
Ki: 2.60nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.60nM
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
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ChEBI
CHEMBL
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(2) dopamine receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Copy SMILES
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Affinity Data
Ki: 2.60nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/TrEMBL
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Ligand Info
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ChEBI
CHEMBL
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
D(2) dopamine receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.60nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/TrEMBL
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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KEGG
PC cid
PC sid
PDB
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Alpha-1A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Copy SMILES
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Affinity Data
Ki: 2.70nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
Copy SMILES
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Affinity Data
Ki: 2.70nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50252513
(9-OH-risperidone | Invega | CHEMBL1621 | 9-hydroxy...)
Copy SMILES
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Affinity Data
Ki: 2.80nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Affinity Data
Ki: 2.90nM
More data for this Ligand-Target Pair
Target Info
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Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50034043
(CHEMBL14376 | 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazo...)
Copy SMILES
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Affinity Data
Ki: 3nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Histamine H1 receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Copy SMILES
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Affinity Data
Ki: 3.10nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
PC cid
PC sid
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM35255
(2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...)
Copy SMILES
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Affinity Data
Ki: 3.20nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50034043
(CHEMBL14376 | 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazo...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.30nM
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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ChEBI
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PC cid
PC sid
Similars
In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Histamine H1 receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM35255
(2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.30nM
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
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ChEBI
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Histamine H1 receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50252513
(9-OH-risperidone | Invega | CHEMBL1621 | 9-hydroxy...)
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Ki: 3.40nM
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Date in BDB:
4/25/2012
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Target
D(2) dopamine receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Ki: 3.77nM
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Date in BDB:
4/25/2012
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Target
5-hydroxytryptamine receptor 1D
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Ki: 3.90nM
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Date in BDB:
4/25/2012
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
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Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
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Ki: 3.90nM
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Date in BDB:
4/25/2012
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)
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Ki: 4.10nM
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4/25/2012
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Target
Histamine H1 receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50048803
(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
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Ki: 4.60nM
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Date in BDB:
4/25/2012
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Ki: 4.80nM
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Date in BDB:
4/25/2012
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PubMed
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Target
Histamine H1 receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Ki: 5.20nM
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Date in BDB:
4/25/2012
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Target
5-hydroxytryptamine receptor 2C
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001786
(1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1...)
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Ki: 6nM
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Date in BDB:
4/25/2012
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PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
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Ki: 6.80nM
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Date in BDB:
4/25/2012
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM35255
(2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...)
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Ki: 7.30nM
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Date in BDB:
4/25/2012
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PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50001885
(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
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Ki: 8nM
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ChEBI
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
D(2) dopamine receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM35255
(2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)t...)
Copy SMILES
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Ki: 8nM
More data for this Ligand-Target Pair
Target Info
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ChEBI
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In Depth
Date in BDB:
4/25/2012
Entry Details
Article
Copy Entry DOI
PubMed
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Target
Alpha-1A adrenergic receptor
(Human)
Mayo Foundation
Curated by
PDSP K
i
Database
Ligand
BDBM50095890
(2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-...)
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Ki: 8.10nM
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Date in BDB:
4/25/2012
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