Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50036867
TargetDihydrofolate reductase(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 2nMAssay Description:Ability to inhibit recombinant human dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50092657(2-[4-(2,4-Diamino-quinazolin-6-ylmethoxycarbonyl)-...)
Affinity DataIC50: 19.3nMAssay Description:Ability to inhibit recombinant rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50092656(2-[4-(2,4-Diamino-pteridin-6-ylmethoxycarbonyl)-be...)
Affinity DataIC50: 120nMAssay Description:Ability to inhibit recombinant rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50092657(2-[4-(2,4-Diamino-quinazolin-6-ylmethoxycarbonyl)-...)
Affinity DataIC50: 125nMAssay Description:Ability to inhibit recombinant human dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50092656(2-[4-(2,4-Diamino-pteridin-6-ylmethoxycarbonyl)-be...)
Affinity DataIC50: 3.10E+3nMAssay Description:Ability to inhibit recombinant human dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed