Compile Data Set for Download or QSAR
Report error Found 106 Enz. Inhib. hit(s) with all data for entry = 50010113
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091178(2-(4-Bromo-thiophen-2-yl)-1-(4-methanesulfonyl-phe...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091197(4-(2-Thiophen-2-yl-4-trifluoromethyl-imidazol-1-yl...)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057987(1-(4-Methanesulfonyl-phenyl)-2-m-tolyl-4-trifluoro...)
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091181(4-[2-(4-Methyl-thiazol-2-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50058001(1-(4-Methanesulfonyl-phenyl)-2-phenyl-4-trifluorom...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057948(1-(4-Methanesulfonyl-phenyl)-2-p-tolyl-4-trifluoro...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057992(2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 280nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091184(4-[2-(6-Methyl-pyridin-3-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 290nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091167(4-[2-(5-Bromo-pyridin-3-yl)-4-trifluoromethyl-imid...)
Affinity DataIC50: 340nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091189(4-[2-(5-Methyl-isoxazol-3-yl)-4-trifluoromethyl-im...)
Affinity DataIC50: 410nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091212(4-[2-(6-Methyl-pyridin-2-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 420nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091188(4-[2-(2-Methyl-thiazol-5-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091176(4-[2-(4-Methyl-pyridin-2-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 440nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091209(4-(2-Pyridin-3-yl-4-trifluoromethyl-imidazol-1-yl)...)
Affinity DataIC50: 440nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091182(1-(4-Methanesulfonyl-phenyl)-2-thiophen-2-yl-4-tri...)
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091207(2-Benzo[1,3]dioxol-4-yl-1-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091166(4-[2-(5-Methyl-pyridin-3-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 510nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091194(4-[2-(2-Methyl-thiazol-4-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 520nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091174(2-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 530nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091192(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 630nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091203(4-[2-(5-Methyl-pyridin-2-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 730nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057921(1-(4-Methanesulfonyl-phenyl)-2-o-tolyl-4-trifluoro...)
Affinity DataIC50: 790nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091180(4-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 940nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091199(3-Bromo-5-[1-(4-methanesulfonyl-phenyl)-4-trifluor...)
Affinity DataIC50: 950nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057992(2-Benzo[1,3]dioxol-5-yl-1-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091201(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091177(1-(4-Methanesulfonyl-phenyl)-2-(3-methyl-thiophen-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091183(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091169(5-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091196(2-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091172(2-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091187(4-[2-(3-Methyl-pyridin-2-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091171(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091200(1-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091168(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091208(5-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091204(4-(4-Difluoromethyl-2-pyridin-3-yl-imidazol-1-yl)-...)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091198(4-[2-(2-Methyl-pyridin-3-yl)-4-trifluoromethyl-imi...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091205(2-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091211(4-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091190(2-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091173(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091179(3-[4-Difluoromethyl-1-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091193(1-(4-Methanesulfonyl-phenyl)-2-pyridin-3-yl-1H-imi...)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50057948(1-(4-Methanesulfonyl-phenyl)-2-p-tolyl-4-trifluoro...)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091183(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091191(3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 3.76E+4nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091169(5-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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