Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 2023
TargetSerine protease 1(Bovine)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16175(CHEMBL108468 | ethyl 4-[3-(3-carbamimidoylphenyl)-...)
Affinity DataKi:  37nM ΔG°:  -42.4kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16175(CHEMBL108468 | ethyl 4-[3-(3-carbamimidoylphenyl)-...)
Affinity DataKi:  410nM ΔG°:  -36.5kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16174(3-[3-(4-beta-alanylpiperazin-1-yl)-3-oxo-2-({[2,4,...)
Affinity DataKi:  600nM ΔG°:  -35.5kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16174(3-[3-(4-beta-alanylpiperazin-1-yl)-3-oxo-2-({[2,4,...)
Affinity DataKi:  640nM ΔG°:  -35.4kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrokinase-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16176(3-adamantan-1-yl-1-[(4-carbamimidamidophenyl)methy...)
Affinity DataKi:  2.40E+3nM ΔG°:  -32.1kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16175(CHEMBL108468 | ethyl 4-[3-(3-carbamimidoylphenyl)-...)
Affinity DataKi:  4.90E+3nM ΔG°:  -30.3kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16173(3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-car...)
Affinity DataKi:  5.30E+3nM ΔG°:  -30.1kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTissue-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16174(3-[3-(4-beta-alanylpiperazin-1-yl)-3-oxo-2-({[2,4,...)
Affinity DataKi:  8.70E+3nM ΔG°:  -28.9kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16173(3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-car...)
Affinity DataKi:  3.20E+4nM ΔG°:  -25.7kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM772(Benzamidine | benzamidine deriv. | [amino(phenyl)m...)
Affinity DataKi:  3.90E+4nM ΔG°:  -25.2kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16176(3-adamantan-1-yl-1-[(4-carbamimidamidophenyl)methy...)
Affinity DataKi:  4.60E+4nM ΔG°:  -24.8kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM772(Benzamidine | benzamidine deriv. | [amino(phenyl)m...)
Affinity DataKi:  1.80E+5nM ΔG°:  -21.4kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM772(Benzamidine | benzamidine deriv. | [amino(phenyl)m...)
Affinity DataKi: >1.00E+6nM ΔG°: >-17.1kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16173(3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-car...)
Affinity DataKi: >1.00E+6nM ΔG°: >-17.1kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Max-Planck-Institut Fuer Biochemie

LigandPNGBDBM16176(3-adamantan-1-yl-1-[(4-carbamimidamidophenyl)methy...)
Affinity DataKi: >1.00E+6nM ΔG°: >-17.1kJ/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2007
Entry Details Article
PubMed