Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50036828
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataEC50:  14nMAssay Description:Human Opioid receptor kappa 1
mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090002(Dynorphin A (1-11)-NH2H-Tyr-Gly-Gly-Phe-Leu-Arg-Ar...)
Affinity DataEC50:  0.740nMAssay Description:Human kOpioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090003(Tyr-Gly-[D-Ala]-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH...)
Affinity DataEC50:  6.10nMAssay Description:Human Opioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090002(Dynorphin A (1-11)-NH2H-Tyr-Gly-Gly-Phe-Leu-Arg-Ar...)
Affinity DataKi:  0.0740nMAssay Description:Binding affinity towards cloned human Opioid receptor kappa 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090003(Tyr-Gly-[D-Ala]-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH...)
Affinity DataKi:  0.150nMAssay Description:Human Opioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataKi:  0.360nMAssay Description:Human Opioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090006([Pro3] Dynorphin A (1-11)-NH2H-Tyr-Gly-Pro-Phe-Leu...)
Affinity DataKi:  2.70nMAssay Description:Human Opioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090002(Dynorphin A (1-11)-NH2H-Tyr-Gly-Gly-Phe-Leu-Arg-Ar...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity towards cloned human Opioid receptor delta 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090006([Pro3] Dynorphin A (1-11)-NH2H-Tyr-Gly-Pro-Phe-Leu...)
Affinity DataKi:  7.5nMAssay Description:Binding affinity at Opioid receptor kappa 1 by to cloned human opioid receptors expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090002(Dynorphin A (1-11)-NH2H-Tyr-Gly-Gly-Phe-Leu-Arg-Ar...)
Affinity DataKi:  7.60nMAssay Description:Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataKi:  19nMAssay Description:Binding affinity towards cloned human Opioid receptor delta 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50369573(CHEMBL1790761)
Affinity DataKi:  55nMAssay Description:Binding affinity of Opioid receptor kappa 1 to cloned human opioid receptor in CHO cell membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM82551(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
Affinity DataKi:  56nMAssay Description:Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090004([D-Pro2] Dynorphin A (1-11)-NH2H-Tyr-D-Pro-Gly-Phe...)
Affinity DataKi:  65nMAssay Description:Human Opioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090003(Tyr-Gly-[D-Ala]-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH...)
Affinity DataKi:  67nMAssay Description:Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090005([Pro2] Dynorphin A (1-11)-NH2H-Tyr-Pro-Gly-Phe-Leu...)
Affinity DataKi:  94nMAssay Description:Human Opioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090009([D-Pro3] Dynorphin A (1-11)-NH2H-Tyr-Gly-D-Pro-Phe...)
Affinity DataKi:  160nMAssay Description:Human Opioid receptor kappa 1 mediated stimulation of [35S]- GTPgammaS binding in CHO cells (Agonist potency).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090003(Tyr-Gly-[D-Ala]-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH...)
Affinity DataKi:  407nMAssay Description:Binding affinity towards cloned human Opioid receptor delta 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090004([D-Pro2] Dynorphin A (1-11)-NH2H-Tyr-D-Pro-Gly-Phe...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090005([Pro2] Dynorphin A (1-11)-NH2H-Tyr-Pro-Gly-Phe-Leu...)
Affinity DataKi:  3.20E+3nMAssay Description:Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090004([D-Pro2] Dynorphin A (1-11)-NH2H-Tyr-D-Pro-Gly-Phe...)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity towards cloned human Opioid receptor delta 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090006([Pro3] Dynorphin A (1-11)-NH2H-Tyr-Gly-Pro-Phe-Leu...)
Affinity DataKi:  5.70E+3nMAssay Description:Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090005([Pro2] Dynorphin A (1-11)-NH2H-Tyr-Pro-Gly-Phe-Leu...)
Affinity DataKi:  6.80E+3nMAssay Description:Binding affinity towards cloned human Opioid receptor delta 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090009([D-Pro3] Dynorphin A (1-11)-NH2H-Tyr-Gly-D-Pro-Phe...)
Affinity DataKi:  7.10E+3nMAssay Description:Binding affinity towards cloned human Opioid receptor delta 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090009([D-Pro3] Dynorphin A (1-11)-NH2H-Tyr-Gly-D-Pro-Phe...)
Affinity DataKi:  8.30E+3nMAssay Description:Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50090006([Pro3] Dynorphin A (1-11)-NH2H-Tyr-Gly-Pro-Phe-Leu...)
Affinity DataKi:  8.80E+3nMAssay Description:Binding affinity towards cloned human Opioid receptor delta 1 in CHO cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed