Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50009922
TargetMetabotropic glutamate receptor 7(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50004881(Amino-(4-phosphono-phenyl)-acetic acid(RS-PPG) | (...)
Affinity DataEC50:  4.80E+4nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50004881(Amino-(4-phosphono-phenyl)-acetic acid(RS-PPG) | (...)
Affinity DataEC50:  4.80E+4nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50004840(CHEMBL22168 | Amino-(4-phosphonomethyl-phenyl)-ace...)
Affinity DataKd:  3.00E+3nMAssay Description:Dissociation constant against N-methyl-D-aspartate glutamate receptor using [3H]CPP binding was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50004881(Amino-(4-phosphono-phenyl)-acetic acid(RS-PPG) | (...)
Affinity DataEC50:  5.20E+3nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50004881(Amino-(4-phosphono-phenyl)-acetic acid(RS-PPG) | (...)
Affinity DataEC50:  3.20E+3nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50007547(CHEMBL440648 | 1-Amino-2-phosphonomethyl-cycloprop...)
Affinity DataEC50:  500nMAssay Description:Effective concentration against Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50089105(1-Amino-3-phosphonomethylene-cyclobutanecarboxylic...)
Affinity DataEC50:  4.50E+3nMAssay Description:Effective concentration against Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed