Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50009887
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088873(2-(8-chloro-2,3-dihydro[1,4]thiazino[2,3,4-hi]indo...)
Affinity DataEC50:  348nMAssay Description:Functional agonist activity of compound was determined by fluorescence-based assay measuring intracellular calcium mobilization for 5-HT2a receptor c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088876(1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrr...)
Affinity DataEC50:  180nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088871(2-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-...)
Affinity DataEC50:  0.200nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088875(2-(2-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinol...)
Affinity DataEC50:  9nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088874(2-(8-fluoro-2,4-dimethyl-5,6-dihydro-4H-pyrrolo[3,...)
Affinity DataEC50:  41nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088872(2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-...)
Affinity DataEC50:  269nMAssay Description:Functional agonist activity of compound was determined by fluorescence-based assay measuring intracellular calcium mobilization for 5-HT2a receptor c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088873(2-(8-chloro-2,3-dihydro[1,4]thiazino[2,3,4-hi]indo...)
Affinity DataEC50:  0.230nMAssay Description:Functional agonist activity of compound was determined by fluorescence-based assay measuring intracellular calcium mobilization for 5-HT2c receptor c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088872(2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-...)
Affinity DataEC50:  5.70nMAssay Description:Functional agonist activity of compound was determined by fluorescence-based assay measuring intracellular calcium mobilization for 5-HT2c receptor c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088876(1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrr...)
Affinity DataEC50:  1.10E+3nMAssay Description:Functional antagonist activity of compound was determined by fluorescence-based assay measuring intracellular calcium mobilization for 5-HT2a recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088871(2-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-...)
Affinity DataEC50:  145nMAssay Description:Functional agonist activity of compound was determined by fluorescence-based assay measuring intracellular calcium mobilization for 5-HT2a receptor c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088876(1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Functional agonist activity of compound was determined by fluorescence-based assay measuring intracellular calcium mobilization for 5-HT2a receptor c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088872(2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088876(1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrr...)
Affinity DataKi:  33nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088871(2-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-...)
Affinity DataKi:  41nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088873(2-(8-chloro-2,3-dihydro[1,4]thiazino[2,3,4-hi]indo...)
Affinity DataKi:  47nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088874(2-(8-fluoro-2,4-dimethyl-5,6-dihydro-4H-pyrrolo[3,...)
Affinity DataKi:  194nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088875(2-(2-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinol...)
Affinity DataKi:  225nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2C receptor expressed in HEK293 cells was determined using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088873(2-(8-chloro-2,3-dihydro[1,4]thiazino[2,3,4-hi]indo...)
Affinity DataKi:  631nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2A receptor expressed in HEK293 cells was determined using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088875(2-(2-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinol...)
Affinity DataKi:  676nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2A receptor expressed in HEK293 cells was determined using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088871(2-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-...)
Affinity DataKi:  794nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2A receptor expressed in HEK293 cells was determined using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088874(2-(8-fluoro-2,4-dimethyl-5,6-dihydro-4H-pyrrolo[3,...)
Affinity DataKi:  954nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2A receptor expressed in HEK293 cells was determined using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088876(1N-methyl-2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrr...)
Affinity DataKi:  1.46E+3nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2A receptor expressed in HEK293 cells was determined using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50088872(2-(8-fluoro-4-methyl-5,6-dihydro-4H-pyrrolo[3,2,1-...)
Affinity DataKi:  2.34E+3nMAssay Description:In vitro binding affinity towards human 5-hydroxytryptamine 2A receptor expressed in HEK293 cells was determined using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed