Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50009860
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088653(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-c...)
Affinity DataKi:  0.0840nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088660(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-c...)
Affinity DataKi:  0.210nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088657(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-i...)
Affinity DataKi:  0.240nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088659(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(3,3-dii...)
Affinity DataKi:  0.270nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088658(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-6-m...)
Affinity DataKi:  0.330nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088655(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-b...)
Affinity DataKi:  0.360nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088652(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-i...)
Affinity DataKi:  0.400nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088656(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-e...)
Affinity DataKi:  1.60nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088661(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((S)-6-m...)
Affinity DataKi:  36nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088654(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methy...)
Affinity DataKi:  350nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088653(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-c...)
Affinity DataKi:  420nMAssay Description:The compound was tested for its ability to inhibit trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088658(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-6-m...)
Affinity DataKi:  510nMAssay Description:The compound was tested for its ability to inhibit trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088652(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-i...)
Affinity DataKi:  580nMAssay Description:The compound was tested for its ability to inhibit trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088660(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-c...)
Affinity DataKi:  770nMAssay Description:The compound was tested for its ability to inhibit trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088657(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-i...)
Affinity DataKi:  860nMAssay Description:The compound was tested for its ability to inhibit trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088659(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(3,3-dii...)
Affinity DataKi:  1.50E+3nMAssay Description:The compound was tested for its ability to inhibit trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088656(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-e...)
Affinity DataKi:  4.20E+3nMAssay Description:The compound was tested for its ability to inhibit trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088655(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-b...)
Affinity DataKi:  1.27E+4nMAssay Description:The compound was tested for its ability to inhibit trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088661(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((S)-6-m...)
Affinity DataKi:  2.20E+4nMAssay Description:The compound was tested for its ability to inhibit trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088654(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(6-methy...)
Affinity DataKi:  1.01E+5nMAssay Description:The compound was tested for its ability to inhibit trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed