Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50009821
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088321(Dimethyl-(tetrahydro-pyran-4-yl)-{4-[(7-p-tolyl-2,...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088302(Dimethyl-(tetrahydro-pyran-4-yl)-(4-{[7-(4-trifluo...)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 1.80nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088322((4-{[7-(4-Ethoxy-phenyl)-2,3-dihydro-benzo[b]oxepi...)
Affinity DataIC50: 1.80nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088319(Dimethyl-(4-{[3-(4-piperidin-1-yl-phenyl)-8,9-dihy...)
Affinity DataIC50: 2.20nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088311(Dimethyl-(tetrahydro-thiopyran-4-yl)-{4-[(7-p-toly...)
Affinity DataIC50: 3.10nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088306((1-Ethyl-propyl)-dimethyl-{4-[(7-p-tolyl-2,3-dihyd...)
Affinity DataIC50: 3.30nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088312(Dimethyl-(4-{[3-(4-pyrrolidin-1-yl-phenyl)-8,9-dih...)
Affinity DataIC50: 3.80nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088325(Dimethyl-(4-oxo-cyclohexyl)-{4-[(7-p-tolyl-2,3-dih...)
Affinity DataIC50: 4.5nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088315((3-Hydroxy-propyl)-dimethyl-{4-[(7-p-tolyl-2,3-dih...)
Affinity DataIC50: 6.80nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088320(1-Methyl-1-{4-[(3-p-tolyl-8,9-dihydro-7H-benzocycl...)
Affinity DataIC50: 25nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 27nMAssay Description:Inhibitory effect on the binding of [125I]- MCP-1 to C-C chemokine receptor type 2-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088309(1-Methyl-1-{4-[(7-p-tolyl-2,3-dihydro-benzo[b]oxep...)
Affinity DataIC50: 43nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088303(1-Methyl-1-(2-{4-[(7-p-tolyl-2,3-dihydro-benzo[b]o...)
Affinity DataIC50: 110nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088308(1-Methyl-1-{4-[(7-p-tolyl-3,4-dihydro-naphthalene-...)
Affinity DataIC50: 240nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088323(1-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...)
Affinity DataIC50: 380nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088317(1-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...)
Affinity DataIC50: 390nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088324(1-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...)
Affinity DataIC50: 430nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088318(1-Methyl-1-{4-[3-(4'-methyl-biphenyl-3-yl)-acryloy...)
Affinity DataIC50: 570nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088316(Tributyl-{4-[3-(4'-methyl-biphenyl-3-yl)-acryloyla...)
Affinity DataIC50: 620nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088305(1-Methyl-1-{4-[(6-p-tolyl-2H-chromene-3-carbonyl)-...)
Affinity DataIC50: 660nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088307(Triethyl-{4-[(7-phenyl-3,4-dihydro-naphthalene-2-c...)
Affinity DataIC50: 840nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088313(1-Methyl-1-(2-{4-[(7-phenyl-3,4-dihydro-naphthalen...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088310(4-Methyl-4-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088314(2-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]RANTESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory effect on the binding of [125I]RANTES to C-C chemokine receptor type 1-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory effect on the binding of [125I]TARC to C-C chemokine receptor type 4-expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory effect on the binding of [125I]- eotaxin to C-C chemokine receptor type 3- expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed