Compile Data Set for Download or QSAR
Report error Found 67 Enz. Inhib. hit(s) with all data for entry = 50035120
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM21842(OFQ 1-17 | N/OFQ | (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-...)
Affinity DataEC50:  63nMAssay Description:pEC50 for its effect on stimulating GTPgammaS binding to membranes of HEK 293 cells overexpressing rat ORL-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087691(8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-s...)
Affinity DataEC50:  38nMAssay Description:pEC50 for its effect on stimulating GTPgammaS binding to membranes of HEK 293 cells overexpressing rat ORL-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087692(8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataEC50:  13nMAssay Description:pEC50 for its effect on stimulating GTPgammaS binding to membranes of HEK 293 cells overexpressing rat ORL-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKd:  4.5nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKd:  3nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM21842(OFQ 1-17 | N/OFQ | (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-...)
Affinity DataKd:  0.100nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087691(8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-s...)
Affinity DataKi:  0.0790nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087692(8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  0.0820nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50057010((S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phen...)
Affinity DataKi:  0.190nMAssay Description:Inhibition against binding of radioligand [Ile5,6-3H]-deltorphin to membrane from baby hamster kidney cells infected with forest virus encoding the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087697(8-Cycloundecyl-1-phenyl-1,3,8-triaza-spiro[4.5]dec...)
Affinity DataKi:  0.210nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087687(8-Cyclononyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  0.240nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087685(8-Cyclododecyl-1-phenyl-1,3,8-triaza-spiro[4.5]dec...)
Affinity DataKi:  0.280nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087698(8-(R)-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro...)
Affinity DataKi:  0.410nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087697(8-Cycloundecyl-1-phenyl-1,3,8-triaza-spiro[4.5]dec...)
Affinity DataKi:  0.490nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087692(8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  0.660nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087697(8-Cycloundecyl-1-phenyl-1,3,8-triaza-spiro[4.5]dec...)
Affinity DataKi:  0.820nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087685(8-Cyclododecyl-1-phenyl-1,3,8-triaza-spiro[4.5]dec...)
Affinity DataKi:  0.950nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087690(8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4....)
Affinity DataKi:  1.5nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087690(8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4....)
Affinity DataKi:  1.5nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087684(8-Cyclooctyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  1.90nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087693(1-Phenyl-8-(4-propyl-cyclohexyl)-1,3,8-triaza-spir...)
Affinity DataKi:  2nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087692(8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  2.10nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087685(8-Cyclododecyl-1-phenyl-1,3,8-triaza-spiro[4.5]dec...)
Affinity DataKi:  2.90nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087691(8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-s...)
Affinity DataKi:  3.20nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087687(8-Cyclononyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  3.20nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087683(8-(4-tert-Butyl-cyclohexyl)-1-phenyl-1,3,8-triaza-...)
Affinity DataKi:  3.30nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087687(8-Cyclononyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  3.90nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087698(8-(R)-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro...)
Affinity DataKi:  4nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087689(8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-s...)
Affinity DataKi:  4.60nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087686(8-Cycloheptyl-1-phenyl-1,3,8-triaza-spiro[4.5]deca...)
Affinity DataKi:  4.70nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087683(8-(4-tert-Butyl-cyclohexyl)-1-phenyl-1,3,8-triaza-...)
Affinity DataKi:  6.70nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087694(8-(4-Methyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spir...)
Affinity DataKi:  7.10nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087693(1-Phenyl-8-(4-propyl-cyclohexyl)-1,3,8-triaza-spir...)
Affinity DataKi:  7.30nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087689(8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-s...)
Affinity DataKi:  8.30nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087684(8-Cyclooctyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  9.10nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087686(8-Cycloheptyl-1-phenyl-1,3,8-triaza-spiro[4.5]deca...)
Affinity DataKi:  12nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087701(8-(4-tert-Butyl-cyclohexyl)-1-phenyl-1,3,8-triaza-...)
Affinity DataKi:  12nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087684(8-Cyclooctyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  13nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087697(8-Cycloundecyl-1-phenyl-1,3,8-triaza-spiro[4.5]dec...)
Affinity DataKi:  15nMAssay Description:Inhibition against binding of radioligand [Ile5,6-3H]-deltorphin to membrane from baby hamster kidney cells infected with forest virus encoding the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087698(8-(R)-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro...)
Affinity DataKi:  20nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087695(8-Cyclohexyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  25nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087691(8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-s...)
Affinity DataKi:  26nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087690(8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4....)
Affinity DataKi:  29nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087689(8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-s...)
Affinity DataKi:  31nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087683(8-(4-tert-Butyl-cyclohexyl)-1-phenyl-1,3,8-triaza-...)
Affinity DataKi:  38nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087699(8-(4-Methyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spir...)
Affinity DataKi:  41nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087692(8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataKi:  46nMAssay Description:Inhibition against binding of radioligand [Ile5,6-3H]-deltorphin to membrane from baby hamster kidney cells infected with forest virus encoding the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087686(8-Cycloheptyl-1-phenyl-1,3,8-triaza-spiro[4.5]deca...)
Affinity DataKi:  51nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087688(1-Phenyl-8-(4-propyl-cyclohexyl)-1,3,8-triaza-spir...)
Affinity DataKi:  52nMAssay Description:Compound was tested for inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087694(8-(4-Methyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spir...)
Affinity DataKi:  57nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
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