Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50009632
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085853(Sodium; [2-cyano-5-(pyridin-4-ylmethoxy)-phenoxy]-...)
Affinity DataIC50: 5nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085845([5-(Benzooxazol-6-ylmethoxy)-2-cyano-phenoxy]-o-to...)
Affinity DataIC50: 6nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085859((2-Chloro-phenyl)-[2-cyano-5-(pyridin-4-ylmethoxy)...)
Affinity DataIC50: 6nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085833(Sodium; [5-(benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-...)
Affinity DataIC50: 7nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085861([5-(Benzooxazol-6-ylmethoxy)-2-cyano-phenoxy]-(2-c...)
Affinity DataIC50: 9nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085831([2-Cyano-5-(pyridin-4-ylmethoxy)-phenoxy]-o-tolyl-...)
Affinity DataIC50: 9nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085830([5-(Benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-phenoxy]...)
Affinity DataIC50: 12nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085838([5-(Benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-phenoxy]...)
Affinity DataIC50: 14nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085855([5-(Benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-phenoxy]...)
Affinity DataIC50: 16nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085840((2-Chloro-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy...)
Affinity DataIC50: 17nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085835([2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-o-tolyl...)
Affinity DataIC50: 20nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085854([2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-(2-fluo...)
Affinity DataIC50: 22nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085832([2-Cyano-5-(2-fluoro-pyridin-4-ylmethoxy)-phenoxy]...)
Affinity DataIC50: 23nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085864([2-Cyano-5-(thiazol-5-ylmethoxy)-phenoxy]-o-tolyl-...)
Affinity DataIC50: 30nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085839([2-Cyano-5-(pyridin-3-ylmethoxy)-phenoxy]-o-tolyl-...)
Affinity DataIC50: 30nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085856([5-(Benzo[1,3]dioxol-5-ylmethoxy)-2-cyano-phenoxy]...)
Affinity DataIC50: 41nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085858((2-Chloro-phenyl)-[2-cyano-5-(pyridazin-4-ylmethox...)
Affinity DataIC50: 44nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085860((5-Benzyloxy-2-cyano-phenoxy)-o-tolyl-acetic acid ...)
Affinity DataIC50: 49nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085844((2-Bromo-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy)...)
Affinity DataIC50: 51nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085837([2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-(2-trif...)
Affinity DataIC50: 53nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085836([2-Cyano-5-(furan-3-ylmethoxy)-phenoxy]-o-tolyl-ac...)
Affinity DataIC50: 68nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085852([2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-phenyl-...)
Affinity DataIC50: 70nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085843([5-(Benzooxazol-5-ylmethoxy)-2-cyano-phenoxy]-o-to...)
Affinity DataIC50: 75nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085863((3-Chloro-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy...)
Affinity DataIC50: 98nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085862([2-Cyano-5-(isothiazol-3-ylmethoxy)-phenoxy]-o-tol...)
Affinity DataIC50: 220nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085841((4-Chloro-phenyl)-[2-cyano-5-(thiophen-3-ylmethoxy...)
Affinity DataIC50: 504nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085848([2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-(2-meth...)
Affinity DataIC50: 529nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085850([2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-thiophe...)
Affinity DataIC50: 630nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085846([2-Cyano-5-(2,6-dimethyl-benzyloxy)-phenoxy]-o-tol...)
Affinity DataIC50: 857nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085847([2-Cyano-5-(2,3-dihydro-benzo[1,4]dioxin-6-ylmetho...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085849([2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-furan-2...)
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085842([2-Cyano-5-(thiophen-3-ylmethoxy)-phenoxy]-furan-3...)
Affinity DataIC50: 2.85E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085857([2-Cyano-5-(pyridin-2-ylmethoxy)-phenoxy]-o-tolyl-...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085834([5-(Benzo[1,3]dioxol-4-ylmethoxy)-2-cyano-phenoxy]...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085851([2-Cyano-5-(3,4,5-trimethoxy-benzyloxy)-phenoxy]-o...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro ability to antagonise the binding of [125I]ET1 to the rat aortic A10 cell membrane endothelin A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed