Compile Data Set for Download or QSAR
Report error Found 104 Enz. Inhib. hit(s) with all data for entry = 50041282
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037463(2-(3-Methoxy-phenyl)-6-morpholin-4-yl-1H-quinolin-...)
Affinity DataIC50: 363nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037454(6-(3-Chloro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin...)
Affinity DataIC50: 372nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037448(6-Dimethylamino-2-(3-methoxy-phenyl)-1H-quinolin-4...)
Affinity DataIC50: 380nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037450(2-(3-Methoxy-phenyl)-6-pyrrolidin-1-yl-1H-quinolin...)
Affinity DataIC50: 437nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409014(CHEMBL50139)
Affinity DataIC50: 447nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50106309(2-(2-fluorophenyl)-6-(pyrrolidin-1-yl)quinolin-4(1...)
Affinity DataIC50: 457nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037462(6-(3-Hydroxy-phenyl)-5H-[1,3]dioxolo[4,5-g]quinoli...)
Affinity DataIC50: 468nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059968(2-(3-fluorophenyl)-7-methyl-1,8-naphthyridin-4(1H)...)
Affinity DataIC50: 525nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037457(6-(3-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin...)
Affinity DataIC50: 525nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059964(6-methyl-2-(naphthalen-1-yl)-1,8-naphthyridin-4(1H...)
Affinity DataIC50: 550nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50056948(Isonicotinic acid 1,2,3-trimethoxy-10-methylsulfan...)
Affinity DataIC50: 562nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037444(6-(3-Methoxy-phenyl)-5H-[1,3]dioxolo[4,5-g]quinoli...)
Affinity DataIC50: 575nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409024(CHEMBL48525)
Affinity DataIC50: 617nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059971(2-(3-Fluoro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50: 631nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037459(6-(3-Methylamino-phenyl)-5H-[1,3]dioxolo[4,5-g]qui...)
Affinity DataIC50: 646nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50009568((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...)
Affinity DataIC50: 646nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059966(7-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50: 661nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50063845((S)-6-(3-Methoxy-phenyl)-6,7-dihydro-5H-[1,3]dioxo...)
Affinity DataIC50: 692nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059961(2-(3-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50: 724nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409011(CHEMBL45711)
Affinity DataIC50: 724nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037453(6-(3-Amino-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-...)
Affinity DataIC50: 724nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059975(2-(3-Fluoro-phenyl)-5,7-dimethyl-1H-[1,8]naphthyri...)
Affinity DataIC50: 741nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50056949(Nicotinic acid 1,2,3-trimethoxy-10-methylsulfanyl-...)
Affinity DataIC50: 759nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059117(2-(3-Methoxy-phenyl)-7-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50: 759nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059978(5,7-Dimethyl-2-naphthalen-1-yl-1H-[1,8]naphthyridi...)
Affinity DataIC50: 776nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059976(2-(3-Chloro-phenyl)-5,7-dimethyl-1H-[1,8]naphthyri...)
Affinity DataIC50: 776nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059111(2-(3-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50: 794nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50037447(6-(3-Trifluoromethyl-phenyl)-5H-[1,3]dioxolo[4,5-g...)
Affinity DataIC50: 813nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059103(2-(3-Methoxy-phenyl)-5,7-dimethyl-1H-[1,8]naphthyr...)
Affinity DataIC50: 871nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059960(2-(3-Chloro-phenyl)-7-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50: 891nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059972(5-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50: 933nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059122(2-(3-Methoxy-phenyl)-1H-[1,8]naphthyridin-4-one | ...)
Affinity DataIC50: 955nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409007(CHEMBL49419)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059969(2-Naphthalen-1-yl-1H-[1,8]naphthyridin-4-one | CHE...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014875(CHEMBL298240 | cid_426728 | 7-Amino-1,2,3-trimetho...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409001(CHEMBL299185)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50041113(2-(3-Methoxy-phenyl)-1H-quinolin-4-one | CHEMBL276...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50056963(4,7,7-Trimethyl-3-oxo-2-oxa-bicyclo[2.2.1]heptane-...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409016(CHEMBL52480)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059959(2-(3-Chloro-phenyl)-1H-[1,8]naphthyridin-4-one | C...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409005(CHEMBL48701)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50064482(N-(2-Hydroxy-1,3-dimethoxy-10-methylsulfanyl-9-oxo...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409017(CHEMBL48462)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081559(2-(5-Bromo-thiophen-2-yl)-7-methyl-1H-[1,8]naphthy...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409021(CHEMBL52534)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059977(6-Methyl-2-m-tolyl-1H-[1,8]naphthyridin-4-one | CH...)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50014853(CHEMBL277998 | cid_434973 | N-(3-Hydroxy-1,2-dimet...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081576(2-(5-Chloro-thiophen-2-yl)-7-methyl-1H-[1,8]naphth...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081560(7-Methyl-2-(5-methyl-thiophen-2-yl)-1H-[1,8]naphth...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50409018(CHEMBL295520)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
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