Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50009453
TargetMu-type opioid receptor(Guinea pig)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083734(2-Amino-N-[(R)-6-(4-hydroxy-benzyl)-3-methyl-2,5,8...)
Affinity DataIC50: 0.110nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083731((6R,9R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propi...)
Affinity DataKi:  0.290nMAssay Description:Compound was tested for binding affinity against mu opioid receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083734(2-Amino-N-[(R)-6-(4-hydroxy-benzyl)-3-methyl-2,5,8...)
Affinity DataIC50: 0.540nMAssay Description:In vitro delta opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in mouse ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083732((6R,9R)-10-((S)-2-Amino-3-phenyl-propionylamino)-7...)
Affinity DataIC50: 9.10nMAssay Description:Compound was tested for its ability to activate mu opioid receptor in GPI bioassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083736(13-((S)-2-Amino-3-phenyl-propionylamino)-7-(4-nitr...)
Affinity DataIC50: 13nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083732((6R,9R)-10-((S)-2-Amino-3-phenyl-propionylamino)-7...)
Affinity DataKi:  14nMAssay Description:Compound was tested for binding affinity against mu opioid receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083730((R)-2-Amino-N-[(S)-6-(4-hydroxy-benzyl)-3-(1H-indo...)
Affinity DataIC50: 17.7nMAssay Description:In vitro delta opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in mouse ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083730((R)-2-Amino-N-[(S)-6-(4-hydroxy-benzyl)-3-(1H-indo...)
Affinity DataIC50: 18nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083729(2-Amino-N-((R)-6-benzyl-3-methyl-2,5,8-trioxo-1,4,...)
Affinity DataIC50: 30nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083729(2-Amino-N-((R)-6-benzyl-3-methyl-2,5,8-trioxo-1,4,...)
Affinity DataIC50: 30.4nMAssay Description:In vitro delta opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in mouse ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083737(13-((S)-2-Amino-3-phenyl-propionylamino)-7-benzyl-...)
Affinity DataIC50: 42nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083733(2-Amino-N-[(S)-6-(4-hydroxy-benzyl)-3-(1H-indol-2-...)
Affinity DataIC50: 627nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083735((R)-2-Amino-N-[(R)-6-(4-hydroxy-benzyl)-3-methyl-2...)
Affinity DataIC50: 1.83E+3nMAssay Description:In vitro mu opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in guinea pi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083733(2-Amino-N-[(S)-6-(4-hydroxy-benzyl)-3-(1H-indol-2-...)
Affinity DataIC50: 8.13E+3nMAssay Description:In vitro delta opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in mouse ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Louisville

Curated by ChEMBL
LigandPNGBDBM50083735((R)-2-Amino-N-[(R)-6-(4-hydroxy-benzyl)-3-methyl-2...)
Affinity DataIC50: 9.33E+3nMAssay Description:In vitro delta opioid activity was determined by its ability to inhibit the electrically induced contractions of smooth muscle preparations in mouse ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed