Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50009292
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)
Affinity DataIC50: 18nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082020(2-Chloro-N-{2-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...)
Affinity DataIC50: 24nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082024(2-{2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quin...)
Affinity DataIC50: 32nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082027(2-Chloro-N-{3-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...)
Affinity DataIC50: 39nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082016(2-Chloro-N-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dihydr...)
Affinity DataIC50: 155nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082023(7-Chloro-4-hydroxy-3-(3-isothiocyanato-phenyl)-1H-...)
Affinity DataIC50: 200nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082022(2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quinoli...)
Affinity DataIC50: 335nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082021(4-Fluorosulfonyl-benzoic acid 7-chloro-2-oxo-3-(3-...)
Affinity DataIC50: 2.41E+3nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082025(4-Hydroxy-7-isothiocyanato-3-(3-phenoxy-phenyl)-1H...)
Affinity DataIC50: 2.40E+4nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082019(2-Chloro-N-[4-hydroxy-2-oxo-3-(3-phenoxy-phenyl)-1...)
Affinity DataIC50: 3.80E+4nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082018(Chloro-acetic acid 7-(2-chloro-acetylamino)-2-oxo-...)
Affinity DataIC50: 6.30E+4nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082017(2-Chloro-N-[7-chloro-2-oxo-3-(3-phenoxy-phenyl)-1,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082020(2-Chloro-N-{2-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082027(2-Chloro-N-{3-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...)
Affinity DataKi:  13.8nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082022(2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quinoli...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082021(4-Fluorosulfonyl-benzoic acid 7-chloro-2-oxo-3-(3-...)
Affinity DataKi:  24.2nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082024(2-{2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quin...)
Affinity DataKi:  26.8nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082016(2-Chloro-N-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dihydr...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082023(7-Chloro-4-hydroxy-3-(3-isothiocyanato-phenyl)-1H-...)
Affinity DataKi:  47.6nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082025(4-Hydroxy-7-isothiocyanato-3-(3-phenoxy-phenyl)-1H...)
Affinity DataKi:  64.3nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082017(2-Chloro-N-[7-chloro-2-oxo-3-(3-phenoxy-phenyl)-1,...)
Affinity DataKi:  216nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082019(2-Chloro-N-[4-hydroxy-2-oxo-3-(3-phenoxy-phenyl)-1...)
Affinity DataKi:  278nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082018(Chloro-acetic acid 7-(2-chloro-acetylamino)-2-oxo-...)
Affinity DataKi:  427nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50082026(4-Hydroxy-2-oxo-3-(3-phenoxy-phenyl)-1,2-dihydro-q...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-5-7 dichlorokynurenic acid ([3H]- DCKA) from N-methyl-D-aspartate glutamate receptor glycine site of rat brain membrane homogena...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed