Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50036762
LigandPNGBDBM50081889(1-[2-(3,3-Diphenyl-propoxy)-ethyl]-1,2,5,6-tetrahy...)
Affinity DataIC50: 48nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081891(1-[2-(3,3-Diphenyl-propoxy)-ethyl]-piperidine-3-ca...)
Affinity DataIC50: 55nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50368628(ABT-569 | Abbott-70569 | Abbott-70569.1 | Gabitril...)
Affinity DataIC50: 67nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081895((R)-1-[3-(3,3-Di-o-tolyl-allyloxy)-propyl]-piperid...)
Affinity DataIC50: 75nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081892((R)-1-[2-(3-Phenyl-3-o-tolyl-propoxy)-ethyl]-piper...)
Affinity DataIC50: 86nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081888((R)-1-[2-(2-Diphenylamino-ethoxy)-ethyl]-piperidin...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50080379((R)-1-[2-(2,2-Diphenyl-vinyloxy)-ethyl]-piperidine...)
Affinity DataIC50: 104nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081901((R)-1-[2-(3,3-Di-o-tolyl-allyloxy)-ethyl]-piperidi...)
Affinity DataIC50: 114nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50080346((R)-1-(2-Benzhydrylideneaminooxy-ethyl)-piperidine...)
Affinity DataIC50: 137nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081887((R)-1-(7-Diphenylamino-heptyl)-piperidine-3-carbox...)
Affinity DataIC50: 232nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081904((R)-1-[2-((E)-3-Phenyl-3-o-tolyl-allyloxy)-ethyl]-...)
Affinity DataIC50: 236nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081899((R)-1-[2-(3,3-Diphenyl-allyloxy)-ethyl]-piperidine...)
Affinity DataIC50: 258nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081881((R)-1-[4-(2-Diphenylamino-ethoxy)-butyl]-piperidin...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50047910(1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxyli...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081882((R)-1-[2-(3,3-Di-o-tolyl-propoxy)-ethyl]-piperidin...)
Affinity DataIC50: 358nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081894((R)-1-(6-Diphenylamino-hexyl)-piperidine-3-carboxy...)
Affinity DataIC50: 659nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081896((R)-1-{2-[3-(4-Fluoro-phenyl)-3-(3-fluoro-phenyl)-...)
Affinity DataIC50: 675nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081897((R)-1-{2-[3,3-Bis-(4-chloro-phenyl)-allyloxy]-ethy...)
Affinity DataIC50: 955nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081880((R)-1-(8-Diphenylamino-octyl)-piperidine-3-carboxy...)
Affinity DataIC50: 1.29E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081879((R)-1-(8,8-Diphenyl-oct-7-enyl)-piperidine-3-carbo...)
Affinity DataIC50: 1.36E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081884((R)-1-(5-Diphenylamino-pentyl)-piperidine-3-carbox...)
Affinity DataIC50: 1.38E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50003653(CHEMBL542610 | 1-(2-Benzhydryloxy-ethyl)-piperidin...)
Affinity DataIC50: 1.41E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081902((R)-1-{2-[3,3-Bis-(4-fluoro-phenyl)-allyloxy]-ethy...)
Affinity DataIC50: 1.46E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081886((R)-1-(6,6-Diphenyl-hexyl)-piperidine-3-carboxylic...)
Affinity DataIC50: 1.59E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081900((R)-1-(6,6-Diphenyl-hex-5-enyl)-piperidine-3-carbo...)
Affinity DataIC50: 2.26E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081883((R)-1-(4-Diphenylamino-butyl)-piperidine-3-carboxy...)
Affinity DataIC50: 2.61E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081903((R)-1-[3-(3-Diphenylamino-propoxy)-propyl]-piperid...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081898((R)-1-{2-[(3,3-Diphenyl-propyl)-methyl-amino]-ethy...)
Affinity DataIC50: 5.70E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081893((R)-1-{2-[2-(2-Diphenylamino-ethoxy)-ethoxy]-ethyl...)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081890((R)-1-(7-Diphenylcarbamoyl-heptyl)-piperidine-3-ca...)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
LigandPNGBDBM50081885((R)-1-(3-Diphenylamino-propyl)-piperidine-3-carbox...)
Affinity DataIC50: 9.00E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed