Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 333
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM705((R)-N-tert-Butyl-3-[(2S,3S)-2-hydroxy-3-(2-methylp...)
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM706((R)-N-tert-Butyl-3-[(2S,3S)-2-hydroxy-3-(3-methylp...)
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM707((R)-N-tert-Butyl-3-[(2S,3S)-2-hydroxy-3-(4-methylp...)
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM704((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-(2-phenox...)
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM709((4R)-N-tert-butyl-3-[(2S,3S)-3-[2-(2-ethyl-6-methy...)
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM710((R)-N-tert-Butyl-3-[(2S,3S)-2-hydroxy-3-(2-methyl-...)
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM711((R)-N-tert-Butyl-3-[(2S,3S)-3-(2,6-diethylpropylph...)
Affinity DatapH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM719(CHEMBL231622 | (4R)-N-tert-butyl-3-[(2S,3S)-2-hydr...)
Affinity DataKi:  0.0880nM ΔG°:  -59.7kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM718((R)-N-(2-Methylbenzyl)-3-[(2S,3S)-3-(2-ethyl-3-hyd...)
Affinity DataKi:  0.160nM ΔG°:  -58.2kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM717((4R)-N-[(2-chlorophenyl)methyl]-3-[(2S,3S)-2-hydro...)
Affinity DataKi:  0.290nM ΔG°:  -56.6kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM580(AG1776 | (4R)-3-[(2S,3S)-2-hydroxy-3-[(3-hydroxy-2...)
Affinity DataKi:  0.330nM ΔG°:  -56.3kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM579(Kynostatin 272 | CHEMBL414640 | (4R)-N-tert-butyl-...)
Affinity DataKi:  0.740nM ΔG°:  -54.2kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM712((R)-N-tert-Butyl-3-[(2S,3S)-3-(2,6-dimethylpropylp...)
Affinity DataKi:  1.40nM ΔG°:  -52.6kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM715((R)-N-tert-Butyl-3-[(2S,3S)-3-(2-ethyl-3-hydroxybe...)
Affinity DataKi:  2.24nM ΔG°:  -51.4kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM714((R)-N-tert-Butyl-3-[(2S,3S)-2-hydroxy-3-(3-hydroxy...)
Affinity DataKi:  5.14nM ΔG°:  -49.2kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM716((R)-N-(2-Methylbenzyl)-3-{(2S,3S)-2-hydroxy-3-(3-h...)
Affinity DataKi:  8.91nM ΔG°:  -47.8kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM708((4R)-N-tert-butyl-3-[(2S,3S)-3-[2-(2,6-dimethylphe...)
Affinity DataKi:  21.7nM ΔG°:  -45.5kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Japan Energy

LigandPNGBDBM713((4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-[(3-hydro...)
Affinity DataKi:  24.9nM ΔG°:  -45.1kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2004
Entry Details Article
PubMed