Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 50035046
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077112(Cis-(3aR,11bS)-10-Trifluoromethyl-1,2,3,3a,4,5,7,1...)
Affinity DataEC50:  9nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077102(6-(3,5-Bis-trifluoromethyl-phenyl)-4-trifluorometh...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403736(CHEMBL2113261)
Affinity DataEC50:  7nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077114(4-Trifluoromethyl-6,7,8,9-tetrahydro-1H-pyrido[3,2...)
Affinity DataEC50:  317nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403735(CHEMBL2113248)
Affinity DataEC50:  56nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077099(Trans-6,7-Dimethyl-4-trifluoromethyl-6,7,8,9-tetra...)
Affinity DataEC50:  10nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403734(CHEMBL2113247)
Affinity DataEC50:  82nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077108(6,6-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...)
Affinity DataEC50:  68nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077110(6,6-Diethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077096(Trans-11-Trifluoromethyl-2,3,4,4a,5,6,8,12b-octahy...)
Affinity DataEC50:  2nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18161(DHT | Dihydrotestosterone | [3H]DHT | (5alpha,17be...)
Affinity DataEC50:  6nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077109(6-Isopropyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1...)
Affinity DataEC50:  3nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077097(6-Methyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-p...)
Affinity DataEC50:  15nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077111(6-Ethyl-1-methyl-4-trifluoromethyl-6,7,8,9-tetrahy...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077094(6-Ethyl-1,9-dimethyl-4-trifluoromethyl-6,7,8,9-tet...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077107(6-Ethyl-9-methyl-4-trifluoromethyl-6,7,8,9-tetrahy...)
Affinity DataEC50:  158nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077104(Cis-(4aR,12bS)-11-Trifluoromethyl-2,3,4,4a,5,6,8,1...)
Affinity DataEC50:  3nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077101(4-Ethyl-8-oxo-6-trifluoromethyl-3,4,8,9-tetrahydro...)
Affinity DataEC50:  137nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18190(Compound 3c | 6-ethyl-4-(trifluoromethyl)-1H,2H,6H...)
Affinity DataEC50:  4nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077100(6-Isobutyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H...)
Affinity DataEC50:  25nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077115(Cis-6,7-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahy...)
Affinity DataEC50:  22nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077105(Trans-6-Ethyl-7-methyl-4-trifluoromethyl-6,7,8,9-t...)
Affinity DataEC50:  7nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077113(6-Propyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-p...)
Affinity DataEC50:  19nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077095(Trans-7-Methyl-4-trifluoromethyl-6-(3,3,3-trifluor...)
Affinity DataEC50:  13nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077114(4-Trifluoromethyl-6,7,8,9-tetrahydro-1H-pyrido[3,2...)
Affinity DataIC50: 12nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077108(6,6-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...)
Affinity DataIC50: 16nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077111(6-Ethyl-1-methyl-4-trifluoromethyl-6,7,8,9-tetrahy...)
Affinity DataIC50: 20nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403735(CHEMBL2113248)
Affinity DataIC50: 29nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077095(Trans-7-Methyl-4-trifluoromethyl-6-(3,3,3-trifluor...)
Affinity DataIC50: 61nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells was determined as a function of maximal inhibition of dihydrotestosterone u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403734(CHEMBL2113247)
Affinity DataIC50: 63nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077110(6,6-Diethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1...)
Affinity DataIC50: 73nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077094(6-Ethyl-1,9-dimethyl-4-trifluoromethyl-6,7,8,9-tet...)
Affinity DataIC50: 216nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077102(6-(3,5-Bis-trifluoromethyl-phenyl)-4-trifluorometh...)
Affinity DataIC50: 251nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077097(6-Methyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-p...)
Affinity DataIC50: 259nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells using cotransfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077105(Trans-6-Ethyl-7-methyl-4-trifluoromethyl-6,7,8,9-t...)
Affinity DataIC50: 2.71E+3nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18190(Compound 3c | 6-ethyl-4-(trifluoromethyl)-1H,2H,6H...)
Affinity DataIC50: 4.58E+3nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells using cotransfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077101(4-Ethyl-8-oxo-6-trifluoromethyl-3,4,8,9-tetrahydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells was determined as a function of maximal inhibition of dihydrotestosterone u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077112(Cis-(3aR,11bS)-10-Trifluoromethyl-1,2,3,3a,4,5,7,1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077099(Trans-6,7-Dimethyl-4-trifluoromethyl-6,7,8,9-tetra...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells was determined as a function of maximal inhibition of dihydrotestosterone u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403736(CHEMBL2113261)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells was determined as a function of maximal inhibition of dihydrotestosterone u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077104(Cis-(4aR,12bS)-11-Trifluoromethyl-2,3,4,4a,5,6,8,1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077096(Trans-11-Trifluoromethyl-2,3,4,4a,5,6,8,12b-octahy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells was determined as a function of maximal inhibition of dihydrotestosterone u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18161(DHT | Dihydrotestosterone | [3H]DHT | (5alpha,17be...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077109(6-Isopropyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells using cotransfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077100(6-Isobutyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells was determined as a function of maximal inhibition of dihydrotestosterone u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077107(6-Ethyl-9-methyl-4-trifluoromethyl-6,7,8,9-tetrahy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells using cotransfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077113(6-Propyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells using cotransfection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077115(Cis-6,7-Dimethyl-4-trifluoromethyl-6,7,8,9-tetrahy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells was determined as a function of maximal inhibition of dihydrotestosterone u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18161(DHT | Dihydrotestosterone | [3H]DHT | (5alpha,17be...)
Affinity DataKi:  2nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077095(Trans-7-Methyl-4-trifluoromethyl-6-(3,3,3-trifluor...)
Affinity DataKi:  2nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
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