Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50035044
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076989((2S,11S,12R)-12-Isobutyl-7-(1-methyl-1H-imidazole-...)
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076992((2S,11S,12R)-7-(4-Amino-benzenesulfonyl)-12-isobut...)
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076990((2S,11S,12R)-12-Isobutyl-13-oxo-7-trifluoromethane...)
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076993(CHEMBL542068 | CHEMBL88220 | (2S,11S,12R)-12-Isobu...)
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076991((2S,11S,12R)-7-Benzenesulfonyl-12-isobutyl-13-oxo-...)
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076991((2S,11S,12R)-7-Benzenesulfonyl-12-isobutyl-13-oxo-...)
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076994((2S,11S,12R)-12-Isobutyl-13-oxo-7-(2,4,6-trimethyl...)
Affinity DataKi: <1nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076992((2S,11S,12R)-7-(4-Amino-benzenesulfonyl)-12-isobut...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076994((2S,11S,12R)-12-Isobutyl-13-oxo-7-(2,4,6-trimethyl...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076989((2S,11S,12R)-12-Isobutyl-7-(1-methyl-1H-imidazole-...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076995((6S,9R,10S)-10-Hydroxycarbamoyl-9-isobutyl-6-methy...)
Affinity DataKi:  3nMAssay Description:Inhibition of MMP-3 (human fibroblast stromelysin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076991((2S,11S,12R)-7-Benzenesulfonyl-12-isobutyl-13-oxo-...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of MMP-3 (human fibroblast stromelysin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076990((2S,11S,12R)-12-Isobutyl-13-oxo-7-trifluoromethane...)
Affinity DataKi:  4nMAssay Description:Inhibition of MMP-1 (human fibroblast collagenase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076989((2S,11S,12R)-12-Isobutyl-7-(1-methyl-1H-imidazole-...)
Affinity DataKi:  12nMAssay Description:Inhibition of MMP-3 (human fibroblast stromelysin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076993(CHEMBL542068 | CHEMBL88220 | (2S,11S,12R)-12-Isobu...)
Affinity DataKi:  13nMAssay Description:Inhibition of MMP-9 (matrix metalloprotease-9, gelatinase B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076994((2S,11S,12R)-12-Isobutyl-13-oxo-7-(2,4,6-trimethyl...)
Affinity DataKi:  15nMAssay Description:Inhibition of MMP-3 (human fibroblast stromelysin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076992((2S,11S,12R)-7-(4-Amino-benzenesulfonyl)-12-isobut...)
Affinity DataKi:  99nMAssay Description:Inhibition of MMP-3 (human fibroblast stromelysin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076990((2S,11S,12R)-12-Isobutyl-13-oxo-7-trifluoromethane...)
Affinity DataKi:  118nMAssay Description:Inhibition of MMP-3 (human fibroblast stromelysin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed