Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50035043
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076948((R)-1-((3R,4R,4aR)-Decahydro-isoquinoline-1-carbon...)
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076945((S)-1-((R)-3-cyclohexyl-2-(ethylsulfonamido)propan...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076949((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076952(3-{[(S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-...)
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076953((R)-1-(3,3-Diphenyl-propionyl)-pyrrolidine-2-carbo...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076951(((R)-2-Cyclohexyl-1-{methyl-[(2-oxo-1-piperidin-4-...)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50038001(CHEMBL1166 | (2R,4S)-1-[5-Guanidino-2-(3-methyl-1,...)
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076946((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Affinity DataIC50: 590nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076954(((R)-2-Cyclohexyl-1-{[(2-oxo-1-piperidin-4-ylmethy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076947((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076945((S)-1-((R)-3-cyclohexyl-2-(ethylsulfonamido)propan...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076948((R)-1-((3R,4R,4aR)-Decahydro-isoquinoline-1-carbon...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076950({(R)-2-Cyclohexyl-1-[(S)-1-(2-oxo-1-piperidin-4-yl...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076946((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076949((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076951(((R)-2-Cyclohexyl-1-{methyl-[(2-oxo-1-piperidin-4-...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076947((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076950({(R)-2-Cyclohexyl-1-[(S)-1-(2-oxo-1-piperidin-4-yl...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076952(3-{[(S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076954(((R)-2-Cyclohexyl-1-{[(2-oxo-1-piperidin-4-ylmethy...)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50076953((R)-1-(3,3-Diphenyl-propionyl)-pyrrolidine-2-carbo...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Research and Development

Curated by ChEMBL
LigandPNGBDBM50038001(CHEMBL1166 | (2R,4S)-1-[5-Guanidino-2-(3-methyl-1,...)
Affinity DataIC50: 1.34E+5nMAssay Description:Inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed