Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50008725
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076511((3R,6R,8aS)-8a-Methyl-5-oxo-6-(3-phenyl-propyl)-he...)
Affinity DataKi:  2nMAssay Description:In vitro inhibitory activity against human thrombin.( Fast moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076511((3R,6R,8aS)-8a-Methyl-5-oxo-6-(3-phenyl-propyl)-he...)
Affinity DataKi:  6nMAssay Description:In vitro inhibitory activity against human thrombin.(Slow moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076509((3R,6S,8aS)-6-Benzyl-5-oxo-hexahydro-thiazolo[3,2-...)
Affinity DataKi:  8nMAssay Description:In vitro inhibitory activity against human thrombin.( Fast moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076507((3R,6S,8aS)-8a-Methyl-5-oxo-6-(2-trifluoromethyl-q...)
Affinity DataKi:  10nMAssay Description:In vitro inhibitory activity against human thrombin.( Fast moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076506((3R,6S,8aS)-6-Benzyl-8a-methyl-5-oxo-hexahydro-thi...)
Affinity DataKi:  16nMAssay Description:In vitro inhibitory activity against human thrombin.( Fast moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076505((3R,6S,8aS)-8a-Methyl-5-oxo-6-(2-trifluoromethyl-q...)
Affinity DataKi:  18nMAssay Description:In vitro inhibitory activity against human thrombin.( Fast moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076513((3R,6S,8aS)-6-Benzyl-8a-methyl-5-oxo-hexahydro-thi...)
Affinity DataKi:  18nMAssay Description:In vitro inhibitory activity against human thrombin.( Fast moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076508((3R,6S,8aS)-8a-Methyl-5-oxo-6-(3-phenyl-propyl)-he...)
Affinity DataKi:  100nMAssay Description:In vitro inhibitory activity against human thrombin.( Fast moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076504((3R,6R,8aS)-8a-Methyl-5-oxo-6-(2-trifluoromethyl-q...)
Affinity DataKi:  150nMAssay Description:In vitro inhibitory activity against human thrombin.( Fast moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076512((3R,6R,8aS)-8a-Methyl-5-oxo-6-phenethyl-hexahydro-...)
Affinity DataKi:  235nMAssay Description:In vitro inhibitory activity against human thrombin.( Fast moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076503((3R,6S,8aS)-8a-Methyl-5-oxo-6-phenethyl-hexahydro-...)
Affinity DataKi:  550nMAssay Description:In vitro inhibitory activity against human thrombin.( Fast moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biochem Therapeutic

Curated by ChEMBL
LigandPNGBDBM50076510((3R,6R,8aS)-6-Benzyl-5-oxo-hexahydro-thiazolo[3,2-...)
Affinity DataKi:  1.11E+3nMAssay Description:In vitro inhibitory activity against human thrombin.( Fast moving component on HPLC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed