Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50008695
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50: 19.3nMAssay Description:Inhibitory concentration against Coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50: 93nMAssay Description:Inhibitory concentration against Tissue type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against coagulation factor VIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50: 251nMAssay Description:Inhibitory concentration against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50: 270nMAssay Description:Inhibitory concentration against coagulation factor VIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50: 270nMAssay Description:Inhibitory concentration against Coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50: 335nMAssay Description:Inhibitory concentration against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50: 415nMAssay Description:Inhibitory concentration against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50: 495nMAssay Description:Inhibitory concentration against Tissue type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076227((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0270nMAssay Description:Inhibitory concentration against trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076227((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0710nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076224((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0730nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076224((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0730nMAssay Description:Inhibitory concentration against trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataKi:  0.230nMAssay Description:Inhibitory concentration against trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076223((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.310nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076225((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.450nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.640nMAssay Description:Inhibitory concentration against trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.650nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataKi:  0.850nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataKi:  0.850nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076228((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  2.40nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  106nMAssay Description:Compound was evaluated for the inhibition of Tissue type plasminogen activator (tissue plasminogen activator)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  140nMAssay Description:Inhibitory concentration against coagulation factor VIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  165nMAssay Description:Inhibitory concentration against Coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  200nMAssay Description:Inhibitory concentration against coagulation factor VIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  385nMAssay Description:Inhibitory concentration against Coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  508nMAssay Description:Inhibitory concentration against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  632nMAssay Description:Inhibitory concentration against Tissue type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  699nMAssay Description:Inhibitory concentration against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  927nMAssay Description:Inhibitory concentration against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  978nMAssay Description:Inhibitory concentration against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076226((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibitory concentration against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed