Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50008649
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075807(1-(3-{1-[2-(4-Iodo-phenyl)-ethyl]-piperidin-4-yl}-...)
Affinity DataKi:  0.0520nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075796(2-Phenoxymethyl-4-(3-piperidin-1-yl-propoxy)-1-{3-...)
Affinity DataKi:  0.106nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075811(3-(4-{3-[2-Phenoxymethyl-4-(3-piperidin-1-yl-propo...)
Affinity DataKi:  0.112nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075803(4-(4-{3-[2-Phenoxymethyl-4-(3-piperidin-1-yl-propo...)
Affinity DataKi:  0.132nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075812(2-Phenoxymethyl-1-{3-[1-((Z)-3-phenyl-allyl)-piper...)
Affinity DataKi:  0.183nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075809(1-[3-(1-Phenethyl-piperidin-4-yl)-propyl]-2-phenox...)
Affinity DataKi:  0.191nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075797(1-{3-[1-(2-Cyclohexyl-ethyl)-piperidin-4-yl]-propy...)
Affinity DataKi:  0.285nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075806(1-{3-[1-(3-Methyl-butyl)-piperidin-4-yl]-propyl}-2...)
Affinity DataKi:  0.290nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075802(4-[2-(4-{3-[2-Phenoxymethyl-4-(3-piperidin-1-yl-pr...)
Affinity DataKi:  0.313nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075799(2-Phenoxymethyl-1-{3-[1-(3-phenyl-propyl)-piperidi...)
Affinity DataKi:  0.361nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075798(1-[3-(1-Cyclohexylmethyl-piperidin-4-yl)-propyl]-2...)
Affinity DataKi:  0.393nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075795(1-[3-(1-But-3-enyl-piperidin-4-yl)-propyl]-2-pheno...)
Affinity DataKi:  0.707nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075808(2-[1,4']Bipiperidinyl-1'-yl-1-[2-(4-chloro-phenoxy...)
Affinity DataKi:  0.75nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075804(1-[3-(1-Isobutyl-piperidin-4-yl)-propyl]-2-phenoxy...)
Affinity DataKi:  0.829nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075800(1-[3-(1-Allyl-piperidin-4-yl)-propyl]-2-phenoxymet...)
Affinity DataKi:  1.60nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075801(1-[3-(1-Methyl-piperidin-4-yl)-propyl]-2-phenoxyme...)
Affinity DataKi:  1.60nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075810(1-[3-(1-Isopropyl-piperidin-4-yl)-propyl]-2-phenox...)
Affinity DataKi:  1.60nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50065468(2-(4-Chloro-phenoxymethyl)-4-(3-piperidin-1-yl-pro...)
Affinity DataKi:  1.70nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50069414(2-(4-Chloro-phenoxymethyl)-4-methyl-1-{3-[1-(3-pip...)
Affinity DataKi:  4.5nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075805(2-Phenoxymethyl-4-(3-piperidin-1-yl-propoxy)-1-(3-...)
Affinity DataKi:  4.5nMAssay Description:Ability to displace [125I]-peptide YY binding to cloned human Neuropeptide Y receptor type 1 expressed in AV-12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed