Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50008645
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075719(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataIC50: 6nMAssay Description:Compound was measured for the inhibition of rat microsomal squalene synthase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052351(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...)
Affinity DataIC50: 16nMAssay Description:Compound was measured for the inhibition of rat microsomal squalene synthase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075719(3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of compound was measured on rat microsomal Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052351(3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...)
Affinity DataIC50: 100nMAssay Description:Inhibition of compound was measured on rat microsomal Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed