Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50008565
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074744(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)
Affinity DataIC50: 38nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074742([3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-4-oxo-4H-...)
Affinity DataIC50: 64nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074745(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)
Affinity DataIC50: 95nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 125nMAssay Description:Inhibition of v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074740(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074741(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074739(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of p60 c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074740(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)
Affinity DataIC50: 2.83E+3nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074740(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074739(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074739(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)
Affinity DataIC50: 4.93E+3nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074744(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of p60 c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074742([3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-4-oxo-4H-...)
Affinity DataIC50: 9.55E+3nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074742([3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-4-oxo-4H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074740(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p60 c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p60 c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074742([3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-4-oxo-4H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p60 c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074742([3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-4-oxo-4H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074741(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074740(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074740(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074744(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074739(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074746(3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM3532(CHEMBL7917 | CHEMBL540068 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50074745(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet-derived growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074744(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074745(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074742([3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-4-oxo-4H-...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074745(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074745(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074741(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)
Affinity DataIC50: 4.52E+4nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Mouse)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074746(3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one | ...)
Affinity DataIC50: 4.62E+4nMAssay Description:Inhibition of EGF-dependent mouse keratinocyte MK cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074748(3-(3-Chloro-phenyl)-7-hydroxy-chromen-4-one | CHEM...)
Affinity DataIC50: 5.88E+4nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074744(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p60 c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074747(3-(3-Chloro-phenyl)-1H-quinolin-4-one | CHEMBL7801)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis

Curated by ChEMBL
LigandPNGBDBM50074746(3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Epidermal growth factor receptor-dependent phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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